MSH6 antibody

Principal name

MSH6 antibody

Alternative names for MSH6 antibody

DNA mismatch repair protein Msh6, GTBP, MutS-alpha 160 kDa subunit, G/T mismatch-binding protein, p160

SwissProt ID

P52701 (Human), P54276 (Mouse), Q03834 (Yeast)

Gene ID

2956 (MSH6)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Bov (Bovine), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), PLA/Proximity ligation assay (PLA), Enzyme Immunoassay (E), Electrophoretic Mobility Shift Assay (EMSA), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of MSH6 antibody

The D mismatch repair system (MMR) repairs post-replication D, inhibits recombition between nonidentical D sequences, and induces both checkpoint and apoptotic responses following certain types of D damage. MSH2 (MutS homologue 2) forms the hMutS-a dimer with MSH6 and is an essential component of the mismatch repair process. hMutS-a is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins, and the Rad50-Mre11-NBS1 complex. Mutations in MSH6 and other MMR proteins have been found in a large proportion of hereditary nonpolyposis colorectal cancer (Lynch Syndrome), the most common form of inherited colorectal cancer in the Western world. Mutations in MSH6 have been shown to occur in glioblastoma in response to temozolomide therapy and to promote temozolomide resistance

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MSH6 antibody

WB Suggested Anti-MSH6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

MSH6 antibody

Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and brain tissues (right) using FYN mouse mAb with DAB staining. Mouse IgG1 3E1 Ascites Hu E, F, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

MSH6 antibody

Human Colon stained with MSH6 Antibody Cat.-No AM12073PU Rabbit IgG SP93 Purified Hu P, WB
0.5 ml / €510.00
  Acris Antibodies GmbH

MSH6 antibody

Human Colon stained with MSH6 Antibody Cat.-No AM12073PU Rabbit IgG SP93 Purified Hu P, WB
1 ml / €730.00
  Acris Antibodies GmbH

MSH6 antibody

Human Colon stained with MSH6 Antibody Cat.-No AM12073PU Rabbit IgG SP93 Purified Hu P, WB
0.1 ml / €290.00
  Acris Antibodies GmbH

MSH6 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between MSH2 and MSH6 HeLa cells were stained with anti-MSH2 rabbit purified polyclonal 1:1200 and anti-MSH6 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG1 1F2 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MSH6 antibody

Human, Mouse, Chicken; Sample Type: Human Colon CancerPrimary Dilution: 1ug/mL; MSH6 antibody - N-terminal region (ARP41348_P050) in Human, Mouse, Chicken cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

MSH6 antibody

Human colon carcinoma stained with Anti-MSH6 antibody. Mouse SPM525 Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

MSH6 antibody

Human colon carcinoma stained with Anti-MSH6 antibody. Mouse SPM525 Purified Hu P
1 ml / €500.00
  Acris Antibodies GmbH

MSH6 antibody

Human colon carcinoma stained with Anti-MSH6 antibody. Mouse SPM525 Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

MSH6 antibody

Human colon carcinoma stained with anti-MSH6 antibody Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

MSH6 antibody

Human colon carcinoma stained with anti-MSH6 antibody Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

MSH6 antibody

Human colon carcinoma stained with anti-MSH6 antibody Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

MSH6 antibody

Western blot analysis of extracts from HUVEC cells, using MSH6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MSH6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PMS2/PMS2CL antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MSH6 antibody

Predicted band size: 153 kDa . Positive control: Hela and 293T cell lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lane1: Hela cell lysate Lane2: 293T cel lysate Lysates: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 45 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MSH6 antibody

Predicted band size: 153 kDa . Positive control: K562 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MSH6 antibody

Western blot analysis of extracts of various cell lines, using MSH6 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSH6 antibody

Western blot analysis using MSH6 antibody Cat.-No AM06411SU-N against truncated MSH6 recombinant protein. Mouse IgG1 3A10H7 Ascites Hu E, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

MSH6 antibody

Immunofluorescence analysis of Hela cells using CDC2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Mouse IgG1 5B11 Ascites Hu E, F, ICC/IF, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

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