MSX1 antibody

Principal name

MSX1 antibody

Alternative names for MSX1 antibody

MSX-1, HOX7, Hox-7, Homeobox protein MSX-1, Homeobox protein Hox-7, Msh homeobox 1-like protein

SwissProt ID

O02786 (Bovin), P13297 (Mouse), P28360 (Human)

Gene ID

4487 (MSX1), 17701 (Msx1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Bov (Bovine), Mky (Monkey), Prim (Primate)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Dot blot (Dot), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MSX1 antibody

In vertebrates the Msx genes are comprise of a small family of chromosomally unlinked homeobox-containing genes related to drosophila gene muscle-segment homeobox (Msh). The pedigree of Msx genes goes back to ancient times, but these genes are expressed in a range of vertebrate tissues including neuronal crest, cranial, sensory placodes, bone and teeth (1). Msx genes have been used as models to study pattern formation and tissue interaction and therefore are growing interest among developmental biologist. Msx proteins have homeodomain, a DNA binding domain that is involved in the transcriptional regulation of key eukaryotic developmental process. The Msx genes bind to DNA as monomers or as homo- and or heterodimers in a DNA sequence specific manner. Beside their presumed role as transcriptional regulators, no other function to these proteins have been ascertained in tissues or embryo. Further understanding of these genes may eventually increase our understanding of how the vertebrate embryo has evolved.
Teeth are vertebrate specific organs, beside variation in tooth number, size and shape many non mammalian vertebrates have multirowed teeth along the mesial to distal and labial to lingual directions whereas mammals develop teeth in single row. Msx1 and Osr2 (odd-skipped related 2) genes play pivotal role in regulating the precise spatiotemporal patterns of sequential tooth development in vertebrates. Msx1 is involved in the activation of odontogenic potential, including Bmp4 expression in the mesenchyme (2). Mice lacking Msx1 exhibited loss of expression of Bmp4 in mesenchymal tissue and molar developmental arrest at the bud stage (2, 3). Bidirectional transcription leading to expression of antisense RNA led to imprinting and transcription inhibition. Msx1 gene function in craniofacial development and specially tooth development where it acts as transcriptional repressor, require antisense RNA regulation (4). In tooth development, the Msx1 is important for dental field determination and tooth morphogenesis, making Msx1 an exemplary model to analyze cell-cell communication leading to early determination of subsequent morphogenesis in mammals. Msx1 is a 297 amino acid protein (approximately 35kDa).

General readings

1. Blin-Wakkach C, Lezot F, Ghoul-Mazgar S, Hotton D, Monteiro S, Teillaud C, Pibouin L, Orestes-Cardoso S, Papagerakis P, Macdougall M, Robert B, Berdal A. Endogenous Msx1 antisense transcript: in vivo and in vitro evidences, structure, and
potential involvement in skeleton development in mammals. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7336-41. Epub 2001 Jun 05. PMID: 11390985

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MSX1 antibody

  Rabbit polyclonal MSX1 Antibody (Center)  
MSX1 Antibody (Center)(Cat. #TA324668) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MSX1 antibody detected the MSX1 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms ICC/IF, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

MSX1 (N-term) antibody

  Goat Anti-MSX1 Antibody  
TA305641 (2.5ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Bov, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

  Rabbit Polyclonal anti-MSX1 antibody  
WB Suggested Anti-MSX1 Antibody Titration: 2.0ug/ml; ELISA Titer: 1:62500; Positive Control: Human Kidney Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

  Rabbit Polyclonal MSX1 Antibody  
Western Blot: MSX1 Antibody [TA337041] - Analysis of human HOX7 in human liver lysate in the 1) absence, 2) presence of immunizing peptide, 3) mouse and 4) rat liver using TA337041 at 2 ug/ml. Rabbit IgG Purified Hu, Ms, Prim, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

  Rabbit Polyclonal Anti-MSX1 Antibody  
WB Suggested Anti-MSX1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

  Mouse Monoclonal anti-Msx-1 Antibody  
MSX1 Mouse IgG1 4F11 Purified Ms ICC/IF, IP, P, WB
100 µl / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

  Rabbit Polyclonal MSX1 Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MSX1 (RC205682, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MSX1. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

Western blot analysis using MSX1 antibody Cat.-No AM06610SU-N against NTERA-2 cell lysate. Mouse IgG1 5D11 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

MSX1 (N-term) antibody

Figure 1. Immunohistochemical analysis of Formalin-Fixed Paraffin-Embedded Human Prostate tissue using AP08779PU-N at 2.5 µg/ml. Goat IgG Aff - Purified Bov, Elephant, Hu, Mky, Ms, Por, Prim, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

MSX1 (N-term) antibody

 MSX1 staining of staining of paraffin embedded Human Prostate(dilution: 2.5µg/ml). Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on data-sheet. Goat IgG Aff - Purified Hu E, P
0.1 mg / €420.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

MSX1 - human gene knockout kit via CRISPR

MSX1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MSX1 - human gene knockout kit via CRISPR

MSX1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MSX1 - human gene knockout kit via CRISPR

MSX1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MSX1 - human gene knockout kit via CRISPR

MSX1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Msx1 - mouse gene knockout kit via CRISPR

Msx1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Msx1 - mouse gene knockout kit via CRISPR

Msx1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Msx1 - mouse gene knockout kit via CRISPR

Msx1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Msx1 - mouse gene knockout kit via CRISPR

Msx1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MSX1

  Recombinant protein of human msh homeobox 1 (MSX1)  
MSX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

MSX1 overexpression lysate

MSX1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

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