MSX1 antibody

Principal name

MSX1 antibody

Alternative names for MSX1 antibody

MSX-1, HOX7, Hox-7, Homeobox protein MSX-1, Homeobox protein Hox-7, Msh homeobox 1-like protein

SwissProt ID

O02786 (Bovin), P13297 (Mouse), P28360 (Human)

Gene ID

4487 (MSX1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Bov (Bovine), Gt (Goat), Prim (Primate)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Dot blot (Dot), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F)

Background of MSX1 antibody

In vertebrates the Msx genes are comprise of a small family of chromosomally unlinked homeobox-containing genes related to drosophila gene muscle-segment homeobox (Msh). The pedigree of Msx genes goes back to ancient times, but these genes are expressed in a range of vertebrate tissues including neuronal crest, cranial, sensory placodes, bone and teeth (1). Msx genes have been used as models to study pattern formation and tissue interaction and therefore are growing interest among developmental biologist. Msx proteins have homeodomain, a DNA binding domain that is involved in the transcriptional regulation of key eukaryotic developmental process. The Msx genes bind to DNA as monomers or as homo- and or heterodimers in a DNA sequence specific manner. Beside their presumed role as transcriptional regulators, no other function to these proteins have been ascertained in tissues or embryo. Further understanding of these genes may eventually increase our understanding of how the vertebrate embryo has evolved.
Teeth are vertebrate specific organs, beside variation in tooth number, size and shape many non mammalian vertebrates have multirowed teeth along the mesial to distal and labial to lingual directions whereas mammals develop teeth in single row. Msx1 and Osr2 (odd-skipped related 2) genes play pivotal role in regulating the precise spatiotemporal patterns of sequential tooth development in vertebrates. Msx1 is involved in the activation of odontogenic potential, including Bmp4 expression in the mesenchyme (2). Mice lacking Msx1 exhibited loss of expression of Bmp4 in mesenchymal tissue and molar developmental arrest at the bud stage (2, 3). Bidirectional transcription leading to expression of antisense RNA led to imprinting and transcription inhibition. Msx1 gene function in craniofacial development and specially tooth development where it acts as transcriptional repressor, require antisense RNA regulation (4). In tooth development, the Msx1 is important for dental field determination and tooth morphogenesis, making Msx1 an exemplary model to analyze cell-cell communication leading to early determination of subsequent morphogenesis in mammals. Msx1 is a 297 amino acid protein (approximately 35kDa).

General readings

Blin-Wakkach C, Lezot F, Ghoul-Mazgar S, Hotton D, Monteiro S, Teillaud C, Pibouin L, Orestes-Cardoso S, Papagerakis P, Macdougall M, Robert B, Berdal A.
Endogenous Msx1 antisense transcript: in vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals.
Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7336-41. Epub 2001 Jun 05.
PMID: 11390985

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MSX1 antibody

MSX1 Antibody (Center)(Cat. #TA324668) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MSX1 antibody detected the MSX1 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms ICC/IF, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

MSX1 (N-term) antibody

TA305641 (2.5ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Bov, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

Western Blot: MSX1 Antibody [TA337041] - Analysis of human HOX7 in human liver lysate in the 1) absence, 2) presence of immunizing peptide, 3) mouse and 4) rat liver using TA337041 at 2 ug/ml. Rabbit IgG Purified Hu, Ms, Prim, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

WB Suggested Anti-MSX1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MSX1 (RC205682, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MSX1. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MSX1 antibody

Western blot analysis using MSX1 antibody Cat.-No AM06610SU-N against NTERA-2 cell lysate. Mouse IgG1 5D11 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

MSX1 (N-term) antibody

Figure 1. Immunohistochemical analysis of Formalin-Fixed Paraffin-Embedded Human Prostate tissue using AP08779PU-N at 2.5 µg/ml. Goat IgG Aff - Purified Bov, Elephant, Hu, Mky, Ms, Por, Prim, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

MSX1 Control Peptide

MSX1
0.25 mg / €250.00
  Acris Antibodies GmbH

MSX1 (46-64) antibody

MSX1 Rabbit Aff - Purified Hu, Ms, Rt Dot, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

MSX1 antibody

MSX1 Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

MSX1 antibody

Western Blot analysis of MSX1 expression in transfected 293T cell line (H00004487-T01) by MSX1 MaxPab polyclonal antibody.

Lane 1: MSX1 transfected lysate(30.90 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

MSX1 antibody

Western Blot analysis of MSX1 expression in transfected 293T cell line (H00004487-T01) by MSX1 MaxPab polyclonal antibody.

Lane 1: MSX1 transfected lysate(30.90 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

MSX1 antibody

MSX1 Mouse IgG2a 2B12 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

MSX1 antibody

MSX1 Mouse IgG2a 3A8 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

MSX1 antibody

MSX1 Mouse IgG2a 1D2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MSX1 antibody

MSX1 Mouse IgG2a 1E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MSX1 antibody

MSX1 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

MSX1 antibody

Human Muscle; HumanMuscle; MSX1 antibody - middle region (ARP31396_T100) in Human Muscle cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

MSX1 (N-term) antibody

 MSX1 staining of staining of paraffin embedded Human Prostate(dilution: 2.5µg/ml). Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on data-sheet. Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Neuromics Antibodies

MSX1 antibody

ELISA: MSX1 Antibody [29880002] Rabbit Hu E
50 µg / €440.00
  Novus Biologicals Inc.

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