MTA1 antibody

Principal name

MTA1 antibody

Alternative names for MTA1 antibody

Metastasis-associated protein MTA1

SwissProt ID

Q13330 (Human), Q62599 (Rat), Q8K4B0 (Mouse)

Gene ID

9112 (MTA1), 64520 (Mta1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Bov (Bovine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of MTA1 antibody

MTA1 (metastasis-associated protein 1) is a component of the NURD (for nucleosome remodeling and histone deacetylation) complex, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity. MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin. Structurally, MTA1 contains a single SH3-binding motif and a zinc finger domain, along with a region similar to the corepressor protein N-Cor. MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis. Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, gastrointestinal and breast carcinomas. Elevated MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, increase mammary cell motility and potentiate growth, and it may, therefore, be an indicator for assessing the potential malignancies of various tumors. A similar protein, MTA1-L1 (MTA1-like protein 1), shares more than 55% sequence homology with MTA1 and is ubiquitously expressed.

General readings

Toh Y, Pencil SD, Nicolson GL.
A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses.
J Biol Chem. 1994 Sep 16;269(37):22958-63.
PMID: 8083195

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTA1 antibody

  Goat Polyclonal Antibody against MTA1  
TA302541 staining (0.03µg/ml) of Human Placenta lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

  Rabbit polyclonal anti-MTA1 antibody  
Western blot analysis of extracts from Jurkat cells, using MTA1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

  Rabbit Polyclonal Anti-MTA1 Antibody  
WB Suggested Anti-MTA1 Antibody Titration: 2.5ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysateMTA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

  Rabbit Polyclonal Anti-MTA1 Antibody  
WB Suggested Anti-MTA1 Antibody Titration: 2.5ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysateMTA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

Western blot (WB) analysis of MTA1 antibody (Cat.-No.: AP06723PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MTA1 antibody

Western blot analysis of MTA1 in 293 cell lysate with SP1395P. Goat Purified Hu WB
0.1 mg / €550.00
  Acris Antibodies GmbH

MTA1 antibody

Western blot analysis of extracts from Jurkat cells, using MTA1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

MTA1 antibody

Western blot analysis of extracts from Jurkat cells, using MTA1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

MTA1 - human gene knockout kit via CRISPR

MTA1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MTA1 - human gene knockout kit via CRISPR

MTA1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MTA1 - human gene knockout kit via CRISPR

MTA1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MTA1 - human gene knockout kit via CRISPR

MTA1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MTA1

  Recombinant protein of human metastasis associated 1 (MTA1)  
MTA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MTA1 (mGFP-tagged) - Human metastasis associated 1 (MTA1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, MTA1 (mGFP-tagged) - Human metastasis associated 1 (MTA1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MTA1 (Myc-DDK tagged) - Human metastasis associated 1 (MTA1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, MTA1 (Myc-DDK tagged) - Human metastasis associated 1 (MTA1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mta1 (GFP-tagged ORF) - Rat metastasis associated 1 (Mta1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mta1 (GFP-tagged ORF) - Rat metastasis associated 1 (Mta1), 200 uL, >10^7 TU/mL  
200 µl / €1,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mta1 (Myc-DDK-tagged ORF) - Rat metastasis associated 1 (Mta1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mta1 (Myc-DDK-tagged ORF) - Rat metastasis associated 1 (Mta1), 200 uL, >10^7 TU/mL  
200 µl / €1,245.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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