MTA1 antibody

Principal name

MTA1 antibody

Alternative names for MTA1 antibody

Metastasis-associated protein MTA1

SwissProt ID

Q13330 (Human), Q62599 (Rat), Q8K4B0 (Mouse)

Gene ID

9112 (MTA1), 829112 (ACA10)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Bov (Bovine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of MTA1 antibody

MTA1 (metastasis-associated protein 1) is a component of the NURD (for nucleosome remodeling and histone deacetylation) complex, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity. MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin. Structurally, MTA1 contains a single SH3-binding motif and a zinc finger domain, along with a region similar to the corepressor protein N-Cor. MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis. Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, gastrointestinal and breast carcinomas. Elevated MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, increase mammary cell motility and potentiate growth, and it may, therefore, be an indicator for assessing the potential malignancies of various tumors. A similar protein, MTA1-L1 (MTA1-like protein 1), shares more than 55% sequence homology with MTA1 and is ubiquitously expressed.

General readings

Toh Y, Pencil SD, Nicolson GL.
A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses.
J Biol Chem. 1994 Sep 16;269(37):22958-63.
PMID: 8083195

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTA1 antibody

Immunoperoxidase of monoclonal antibody to MTA1 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 1.2 ug/ml] Mouse IgG3 4D5 Purified Hu, Ms, Rt E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

Immunofluorescence of monoclonal antibody to MTA1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG3 4D11 Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

TA302541 staining (0.03µg/ml) of Human Placenta lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

Western blot analysis of extracts from Jurkat cells, using MTA1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

WB Suggested Anti-MTA1 Antibody Titration: 2.5ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysateMTA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

WB Suggested Anti-MTA1 Antibody Titration: 2.5ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysateMTA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA1 antibody

Western blot (WB) analysis of MTA1 antibody (Cat.-No.: AP06723PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MTA1 antibody

Western blot analysis of MTA1 in 293 cell lysate with SP1395P. Goat Purified Hu WB
0.1 mg / €550.00
  Acris Antibodies GmbH

MTA1 antibody

MTA1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MTA1 antibody

Western Blot analysis of MTA1 expression in transfected 293T cell line by MTA1 MaxPab rabbit polyclonal antibody.

Lane 1: MTA1 transfected lysate(28.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 Mouse IgG2a 2D4 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 Mouse IgG1 3A3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 monoclonal antibody (M10), clone 1C3. Western Blot analysis of MTA1 expression in A-549 ( Cat # L025V1 ). Mouse IgG2a 1C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 monoclonal antibody (M10), clone 1C3. Western Blot analysis of MTA1 expression in U-2 OS ( Cat # L022V1 ). Mouse IgG2a 1C3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 Mouse IgG1 3E7 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 Mouse IgG1 1F12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

MTA1 antibody

MTA1 polyclonal antibody ( Cat # PAB6053 ) staining ( 0.03 µg/ml ) of human placenta lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

MTA1 antibody

Western blot analysis of extracts from Jurkat cells, using MTA1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

MTA1 antibody

Western blot analysis of extracts from Jurkat cells, using MTA1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

MTA1 antibody

Human Jurkat; WB Suggested Anti-MTA1 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate. MTA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; MTA1 antibody - middle region (ARP37737_T100) in Human Jurkat cells using Western Blot Rabbit IgG Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

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