MTA2 antibody

Principal name

MTA2 antibody

Alternative names for MTA2 antibody

MTA1L1, MTA1-L1, PID, Metastasis-associated protein MTA2, Metastasis-associated 1-like 1, p53 target protein in deacetylase complex

SwissProt ID

O94776 (Human), Q9R190 (Mouse)

Gene ID

23942 (Mta2), 9219 (MTA2)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), African clawed frog, Chimp (Chimpanzee), Mky (Monkey), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit), Ye (Yeast)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of MTA2 antibody

MTA2 has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Blackshaw,S., et al., (2004) PLoS Biol. 2 (9), E247 (2004)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTA2 antibody

  Rabbit Polyclonal PID Antibody  
Western blot analysis of PID expression in HeLa whole cell lysates in the absence (A) or presence (B) of blocking peptide with PID antibody at 1 ug /ml. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA2 (C-term) antibody

  Rabbit polyclonal PID/MTA2 Antibody (C-term)  
PID/MTA2 Antibody (C-term) (Cat. #TA324856) western blot analysis in Hela cell line and mouse brain tissue lysates (35ug/lane).This demonstrates the PID/MTA2 antibody detected the PID/MTA2 protein (arrow). Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal Anti-MTA2 Antibody  
WB Suggested Anti-MTA2 Antibody Titration: 1.25ug/ml; Positive Control: Jurkat cell lysate; MTA2 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal Anti-MTA2 Antibody  
WB Suggested Anti-MTA2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal Anti-MTA2 Antibody  
WB Suggested Anti-MTA2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate MTA2 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal Anti-MTA2 Antibody  
WB Suggested Anti-MTA2 Antibody Titration: 5.0 ug/ml; ELISA Titer: 1:312500; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal Anti-Mta2 Antibody  
WB Suggested Anti-Mta2 Antibody Titration: 0.725 ug/ml; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal Anti-MTA2 Antibody  
WB Suggested Anti-MTA2 Antibody Titration: 1.25 ug/ml; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

  Rabbit Polyclonal MTA2 Antibody  
WB was performed on nuclear extracts from HeLa cells (HeLa NE , 20 ug) using the antibody against MTA2 diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (in kDa) is shown on the left; the location of the protein of interest is indicated on the right. Rabbit IgG Purified Hu
50 µg / €325.00
  OriGene Technologies, Inc.

MTA2 antibody

Western blot analysis of PID/MTA2 expression in HeLa whole cell lysates in the absence (A) or presence (B) of blocking peptide with PID antibody at 1 µg /ml. Rabbit IgG Purified Hu, Ms, Rt C, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

MTA2 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Prostate. Rabbit Purified Hu, Ms, Rt ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

MTA2 - human gene knockout kit via CRISPR

MTA2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MTA2 - human gene knockout kit via CRISPR

MTA2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MTA2 - human gene knockout kit via CRISPR

MTA2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MTA2 - human gene knockout kit via CRISPR

MTA2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mta2 - mouse gene knockout kit via CRISPR

Mta2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mta2 - mouse gene knockout kit via CRISPR

Mta2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mta2 - mouse gene knockout kit via CRISPR

Mta2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mta2 - mouse gene knockout kit via CRISPR

Mta2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MTA2 (mGFP-tagged)-Human metastasis associated 1 family, member 2 (MTA2), 200 uL, >10^7 TU/mL

Lenti ORF particles, MTA2 (mGFP-tagged)-Human metastasis associated 1 family, member 2 (MTA2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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