MTBP antibody

Principal name

MTBP antibody

Alternative names for MTBP antibody

Mdm2-binding protein, hMTBP, Mdm2

SwissProt ID

Q8BJS8 (Mouse), Q96DY7 (Human)

Gene ID

27085 (MTBP), 1027085 (argR)

Available reactivities

Hu (Human), Ms (Mouse), Chimp (Chimpanzee), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of MTBP antibody

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2 (1), p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), PID/MTA2 (6) and MTBP (7), were recently discovered. The transcriptional activity of p53 is modulated by posttranslational regulations of the p53 protein including stabilization and acetylation. P53 transcriptionally activatesMDM2 gene then the translated MDM2 protein binds to p53and promotes the degradation of p53 leading to lowering the concentration of p53 protein. MDM2 inhibits both p53mediated G1 arrest and apoptosis. A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53 (7). MTBP is expressed in a variety of normal tissues (7).

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTBP (Center) antibody

Western blot analysis of MTBP expression in K562 whole cell lysates with MTBP antibody at 1 ug /ml. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MTBP antibody

Host: Rabbit; Target Name: MTBP; Sample Tissue: 293T Whole cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MTBP (667-812) antibody

Western blot using anti-MTBP antibody shows detection of a band ~110 kDa corresponding to human MTBP (arrowhead). Lanes represent human 293 cell lysates with (+) and without (-) transfection with a full-length human expression MTBP construct. The transfected cell extract was diluted 30 fold in extract lacking transfected MTBP. Proteins were separated by SDS-PAGE and transferred onto PDVF membrane. After blocking, the membrane was probed with the primary antibody diluted to 1:500 for 2h at room temperature followed by detection using a Lumi-LightPlus Western Blotting Kit (Roche). Mouse IgG1 PHL-1 Ascites Chimp, Hu E, WB
0.1 ml / €440.00
  Acris Antibodies GmbH

MTBP (C-term) antibody

Western blot analysis of MTBP antibody (C-term) (AP17569PU-N) in K562 cell line lysates (35ug/lane). MTBP (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MTBP Control Peptide

MTBP
50 µg / €160.00
  Acris Antibodies GmbH

MTBP (122-139) antibody

Immunocytochemical staining of K562 cells with Rabbit anti Human MTBP (SP1310) Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

MTBP antibody

Western blot using MTBP monoclonal antibody, clone PHL-1 ( Cat # MAB1995 ) shows detection of aband ~110 kDa corresponding to human MTBP ( arrowhead ).
Lanes represent human 293 cell lysates with ( + ) and without ( - ) transfection with a full-length human expression MTBP construct.
The transfected cell extract was diluted 30 fold in extract lacking transfected MTBP.
Proteins were separated bySDS-PAGE and transferred onto PDVF membrane.
After blocking, the membrane was probed with the primary antibody diluted to 1 : 500 for 2h at roomtemperature followed by detection usinga Lumi-Light Plus Western Blotting Kit. Chimp, Hu
0.1 ml / €560.00
  Abnova Taiwan Corp.

MTBP antibody

Western blot analysis of MTBP expression in K-562 whole cell lysates with MTBP polyclonal antibody ( Cat # PAB10134 ) at 1 µg /ml. Hu
0.1 mg / €470.00
  Abnova Taiwan Corp.

MTBP antibody

Immunohistochemistry-Paraffin: MTBP Antibody [NBP1-76747] - K562 cells with MTBP antibody at 5 u/mL._x000d_ Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

MTBP antibody

Immunohistochemistry-Paraffin: MTBP Antibody [NBP1-86408] Immunohistochemical staining of human cerebellum shows strong nuclear positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MTBP overexpression lysate

MTBP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

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