MTMR15 antibody

Principal name

MTMR15 antibody

Alternative names for MTMR15 antibody

KIAA1018, Coiled-coil domain-containing protein MTMR15

SwissProt ID

Q69ZT1 (Mouse), Q9Y2M0 (Human)

Gene ID

22909 (FAN1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of MTMR15 antibody

Nuclease required for maintenance of chromosomal stability. Plays a key role in DNA repair of DNA interstrand cross-links (ICL) by being recruited to sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, possibly in the resolution of homologous recombination intermediates. Not involved in DNA double-strand breaks resection. Has both endonuclease activity toward 5'-flaps and 5'-exonuclease activity: may act in concert with the 3'-flap-specific enzymes to unhook the ICL by cleaving the lagging-strand template.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTMR15 antibody

Immunofluorescence of purified MaxPab antibody to MTMR15 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MTMR15 293T Cell Transient Overexpression Lysate(Denatured)

MTMR15 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

2 Item(s)

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