MTMR15 antibody

Principal name

MTMR15 antibody

Alternative names for MTMR15 antibody

KIAA1018, Coiled-coil domain-containing protein MTMR15

SwissProt ID

Q69ZT1 (Mouse), Q9Y2M0 (Human)

Gene ID

22909 (FAN1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of MTMR15 antibody

Nuclease required for maintenance of chromosomal stability. Plays a key role in DNA repair of DNA interstrand cross-links (ICL) by being recruited to sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, possibly in the resolution of homologous recombination intermediates. Not involved in DNA double-strand breaks resection. Has both endonuclease activity toward 5'-flaps and 5'-exonuclease activity: may act in concert with the 3'-flap-specific enzymes to unhook the ICL by cleaving the lagging-strand template.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTMR15 antibody

Immunofluorescence of purified MaxPab antibody to MTMR15 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

MTMR15 antibody

Western Blot: MTMR15 Antibody [NBP1-42677]-Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-MTMR15 antibody used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  MTMR15 was also immunoprecipitated by another rabbit anti-MTMR15 antibody, which recognizes a downstream epitope. Rabbit Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

MTMR15 antibody

Immunohistochemistry-Paraffin: MTMR15 Antibody [NBP1-87891] Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in non-germinal center cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MTMR15 293T Cell Transient Overexpression Lysate(Denatured)

MTMR15 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

4 Item(s)

per page
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