MTSS1-like protein / MTSS1L antibody

Principal name

MTSS1-like protein / MTSS1L antibody

Alternative names for MTSS1-like protein / MTSS1L antibody

Actin-bundling with BAIAP2 homology protein 1, ABBA-1

Gene ID

92154 (MTSS1L)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Western blot / Immunoblot (WB)

Background of MTSS1-like protein / MTSS1L antibody

Radial glia play key roles in neuronal migration, axon guidance, and neurogenesis during development of the central nervous system. However, the molecular mechanisms regulating growth and morphology of these extended cells are unknown. ABBA, a novel member of the IRSp53/MIM protein family, is enriched in different types of radial glia. ABBA binds ATP-actin monomers with high affinity and deforms PIP2-rich membranes in vitro through its WH2 and IMdomains, respectively. In radial glia-like C6-R cells, ABBA localizes to the interface between the actin cytoskeleton and plasma membrane, and its depletion by RNAi leads to defects in lamellipodial dynamics and process extension. Together, ABBA acts as a novel regulator of actin and plasma membrane dynamics in radial glial cells, and provides evidence that the membrane binding/deformation activity is critical for the cellular functions of IRSp53/MIM/ABBA family proteins.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MTSS1-like protein / MTSS1L antibody

Host: Rabbit; Target Name: MTSS1L; Sample Tissue: OVCAR-3 Whole Cell lysates; Antibody Dilution: 1.0 ug/mlMTSS1L is supported by BioGPS gene expression data to be expressed in OVCAR3 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MTSS1-like protein / MTSS1L antibody

MTSS1-like protein / MTSS1L Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MTSS1-like protein / MTSS1L

MTSS1-like protein / MTSS1L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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