Mucin-4 antibody

Principal name

Mucin-4 antibody

Alternative names for Mucin-4 antibody

MUC4, MUC-4, ASGP, Pancreatic adenocarcinoma mucin, Testis mucin, Ascites sialoglycoprotein, Tracheobronchial mucin

SwissProt ID

Q63661 (Rat), Q8JZM8 (Mouse), Q99102 (Human)

Gene ID

4585 (MUC4)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Mucin-4 antibody

MUC4 is a membrane-associated protein of the mucin (MUC) gene family, encoded by a gene on chromosome 3q29 and produced by epithelial cells as a heterodimer. The MUC4 protein is thought to play a protective role for vulnerable epithelia, particularly in the airway, eye, female reproductive tract and mammary gland. Two observations support this hypothesis: (a) MUC4 acts as an anti-adhesive barrier at epithelial and tumor surfaces, and (b) MUC4 binds the receptor tyrosine kinase ErbB2, and can alter its downstream signaling. Alterations in MUC4 expression have been observed in association with a variety of inflammatory and neoplastic states; reduction or loss has been reported in non-small cell lung carcinoma, hyperplastic polyps of the colon, and serrated colon adenomas, while overexpression of the MUC4/Sialomucin complex (SMC) has been identified in malignant progression of mammary tumors in both humans and rats.

General readings

Soto, P et al. Enzymatic cleavage as a processing step in the maturation of Muc4/sialomucin complex. J Cell Biochem. 15;97(6):1267-74. (2006)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Mucin-4 antibody

HUVEC cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with purified clone 1G8.  Proteins were visualized using an HRP goat anti-mouse secondary antibody and a chemiluminescent detection system. Mouse IgG 1G8 Purified Hu, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Mucin-4 antibody

HUVEC cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with purified clone 1G8.  Proteins were visualized using an HRP goat anti-mouse secondary antibody and a chemiluminescent detection system. Mouse IgG 1G8 Purified Hu, Rt WB
25 µg / €240.00
  Acris Antibodies GmbH

Mucin-4 antibody

Western Blot: MUC4 Antibody - WB analysis of MUC4  beta in A. MCF7 whole cell extract and B. HeLa whole cell extract. Rabbit Purified Hu, Ms C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Mucin-4 antibody

Mucin-4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Mucin-4 antibody

Immunoperoxidase of monoclonal antibody to MUC4 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml] Mouse IgG2a 5B12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Mucin-4 antibody

Western blot analysis of MUC4 expression in Hela (A); SP2/0 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Mucin-4 antibody

Western blot analysis of MUC4 expression in Hela (A); SP2/0 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Mucin-4 antibody

Western blot analysis of MUC4 expression in Hela (A); SP2/0 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Mucin-4 antibody

Mucin-4 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

Mucin-4 antibody

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505] - Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505] Immunohistochemical staining of human colon shows strong cytoplasmic positivity in goblet cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Mucin-4

Mucin-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Mucin-4

Mucin-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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