Muscarinic acetylcholine receptor M1 antibody

Principal name

Muscarinic acetylcholine receptor M1 antibody

Alternative names for Muscarinic acetylcholine receptor M1 antibody

CHRM1, mAChR M1, mAChR-M1

SwissProt ID

P04761 (Pig), P08482 (Rat), P11229 (Human), P12657 (Mouse)

Gene ID

25229 (Chrm1), 1128 (CHRM1)

Available reactivities

Rt (Rat), Bov (Bovine), Hu (Human), Ms (Mouse), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Muscarinic acetylcholine receptor M1 antibody

The action of the neurotransmitter acetylcholine is mediated through two types of receptors, the ionotrophic nicotinic receptors and the metabotrophic muscarinic receptors. The muscarinic receptors belong to the superfamily of 7-TM G-protein-coupled receptors. Five subtypes of muscarinic receptors have been cloned and med m1-m5. The muscarinic receptors are widely distributed throughout the body, but are predomintly expressed within the parasympathetic nervous system and exerts both excitatory and inhibitory control over central and peripheral tissues. Muscarinic receptors participate in a number of physiological functions such as regulation of heart rate, muscle contraction, cognition, sensory processing and motor control. They also participate in learning and memory processing. The m1 receptors are the most abundant muscarinic subtype in the cortex and striatum. m1 receptors were also localized in the myenteric plexus where they function as autoreceptors to enhance the release of Ach from the nerves. The m1, m3 and m5 receptors, which are coupled to Gq/11 proteins, can protect cells from undergoing apoptosis induced by D damage. The sigling mechanism that mediates this anti-apoptotic response is still poorly understood. However, it was recently reported that a poly-basic motif in the C-terminus tail of the m1, m3 and m5 receptors is an essential element for the anti-apoptotic response of those receptors.

General readings

General / background references:Ladner CJ & Lee JM Reduced high-affinity agonist binding at the M(1) muscarinic receptor in Alzheimer's disease brain: differential sensitivity to agonists and divalent cations. Exp Neurol 158:451-8 (1999). PubMed PMID: 10415152
Wang P et al. Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. J Pharmacol Exp Ther 273:959-66 (1995). PubMed PMID: 7752101

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Muscarinic acetylcholine receptor M1 (C-term) antibody

TA302450 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of extracts of HepG2 cell lines, using CHRM1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of rat brain membranes: 1. Anti-M1 Muscarinic Receptor antibody, (1:200). 2. Anti-M1 Muscarinic Receptor antibody, preincubated with the control fusion protein antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of rat brain lysate: 1. Anti-M1 Muscarinic Receptor (443-458) antibody, (1:200). 2. Anti-M1 Muscarinic Receptor (443-458) antibody, preincubated with the control antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

WB Suggested Anti-CHRM1 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Bladder Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis with extracts from HeLa cells using Muscarinic acetylcholine receptor M1 antibody Cat.-No. AP01261PU-N (1/500). Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Muscarinic acetylcholine receptor M1 antibody

CHRM1 polyclonal antibody ( Cat # PAB7100 ) ( 1 µg/ml ) staining of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of extracts from HepG2 cells, using CHRM1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of extracts from HepG2 cells, using CHRM1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Muscarinic acetylcholine receptor M1 antibody

Western Blot: CHRM1 Antibody [NB100-41399] - NB100-41399 (1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Muscarinic acetylcholine receptor M1 antibody

Western Blot: Muscarinic Acetylcholine Receptor M1 Antibody [NB300-628] - Figure 1 shows a Western blot on recombinant m1AChR using NB300-628. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.2 mg / €400.00
  Novus Biologicals Inc.

Muscarinic acetylcholine receptor M1 antibody

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor 1 Antibody [NBP1-87466] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Muscarinic acetylcholine receptor M1

Muscarinic acetylcholine receptor M1 Human
10 µg / €540.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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