Muscarinic acetylcholine receptor M1 antibody

Principal name

Muscarinic acetylcholine receptor M1 antibody

Alternative names for Muscarinic acetylcholine receptor M1 antibody

CHRM1, mAChR M1, mAChR-M1

SwissProt ID

P04761 (Pig), P08482 (Rat), P11229 (Human), P12657 (Mouse)

Gene ID

1128 (CHRM1), 12669 (Chrm1), 25229

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Muscarinic acetylcholine receptor M1 antibody

The action of the neurotransmitter acetylcholine is mediated through two types of receptors, the ionotrophic nicotinic receptors and the metabotrophic muscarinic receptors. The muscarinic receptors belong to the superfamily of 7-TM G-protein-coupled receptors. Five subtypes of muscarinic receptors have been cloned and med m1-m5. The muscarinic receptors are widely distributed throughout the body, but are predomintly expressed within the parasympathetic nervous system and exerts both excitatory and inhibitory control over central and peripheral tissues. Muscarinic receptors participate in a number of physiological functions such as regulation of heart rate, muscle contraction, cognition, sensory processing and motor control. They also participate in learning and memory processing. The m1 receptors are the most abundant muscarinic subtype in the cortex and striatum. m1 receptors were also localized in the myenteric plexus where they function as autoreceptors to enhance the release of Ach from the nerves. The m1, m3 and m5 receptors, which are coupled to Gq/11 proteins, can protect cells from undergoing apoptosis induced by D damage. The sigling mechanism that mediates this anti-apoptotic response is still poorly understood. However, it was recently reported that a poly-basic motif in the C-terminus tail of the m1, m3 and m5 receptors is an essential element for the anti-apoptotic response of those receptors.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Muscarinic acetylcholine receptor M1 (C-term) antibody

TA302450 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Muscarinic acetylcholine receptor M1 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of extracts of HepG2 cell lines, using CHRM1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of rat brain membranes: 1. Anti-M1 Muscarinic Receptor antibody, (1:200). 2. Anti-M1 Muscarinic Receptor antibody, preincubated with the control fusion protein antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of rat brain lysate: 1. Anti-M1 Muscarinic Receptor (443-458) antibody, (1:200). 2. Anti-M1 Muscarinic Receptor (443-458) antibody, preincubated with the control antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

WB Suggested Anti-CHRM1 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Bladder Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (CHRM1 Antibody) at dilution 1/375, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (CHRM1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis with extracts from HeLa cells using Muscarinic acetylcholine receptor M1 antibody Cat.-No. AP01261PU-N (1/500). Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Muscarinic acetylcholine receptor M1 antibody

CHRM1 polyclonal antibody ( Cat # PAB7100 ) ( 1 µg/ml ) staining of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of extracts from HepG2 cells, using CHRM1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Muscarinic acetylcholine receptor M1 antibody

Western blot analysis of extracts from HepG2 cells, using CHRM1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Chrm1 - mouse gene knockout kit via CRISPR

Chrm1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Chrm1 - mouse gene knockout kit via CRISPR

Chrm1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chrm1 - mouse gene knockout kit via CRISPR

Chrm1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chrm1 - mouse gene knockout kit via CRISPR

Chrm1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Muscarinic acetylcholine receptor M1

Muscarinic acetylcholine receptor M1 Human
10 µg / €540.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CHRM1 (mGFP-tagged) - Human cholinergic receptor, muscarinic 1 (CHRM1), 200 uL, >10^7 TU/mL

Lenti ORF particles, CHRM1 (mGFP-tagged) - Human cholinergic receptor, muscarinic 1 (CHRM1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CHRM1 (Myc-DDK tagged) - Human cholinergic receptor, muscarinic 1 (CHRM1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CHRM1 (Myc-DDK tagged) - Human cholinergic receptor, muscarinic 1 (CHRM1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Chrm1 (GFP-tagged) - Mouse cholinergic receptor, muscarinic 1, CNS (Chrm1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Chrm1 (GFP-tagged) - Mouse cholinergic receptor, muscarinic 1, CNS (Chrm1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.

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