MUSK antibody

Principal name

MUSK antibody

Alternative names for MUSK antibody

Muscle-specific kinase receptor, Muscle, skeletal receptor tyrosine-protein kinase

SwissProt ID

O15146 (Human), Q61006 (Mouse), Q62838 (Rat), Q8AXY6 (Chick)

Gene ID

18198 (Musk), 81725, 4593 (MUSK)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human)

Available hosts

Rabbit, Goat, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MUSK antibody

Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between
the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of
MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes
including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine
receptors (AChR) in the postsynaptic membrane.

General readings

General / background references:Hopf C & Hoch W Tyrosine phosphorylation of the muscle-specific kinase is exclusively induced by acetylcholine receptor-aggregating agrin fragments. Eur J Biochem 253:382-9 (1998). PubMed PMID: 9654087
Hopf C & Hoch W Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes. J Biol Chem 273:6467-73 (1998). PubMed PMID: 9497380
Montanaro F et al. Laminin and alpha-dystroglycan mediate acetylcholine receptor aggregation via a MuSK-independent pathway. J Neurosci 18:1250-60 (1998). PubMed PMID: 9454835

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MUSK (N-term) antibody

Western blot analysis of MUSK Antibody (N-term) (Cat. #TA324965) in Jurkat cell line lysates (35ug/lane). MUSK (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

MUSK antibody

Western blot analysis of extracts of SW480 cell line, using MUSK antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MUSK antibody

Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using MUSK antibody Cat.-No AM06338SU-N with DAB staining. Mouse IgG1 10A4 Ascites Hu E, ICC/IF, P
0.1 ml / €400.00
  Acris Antibodies GmbH

MUSK (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MUSK antibody

Western blot analysis of anti-MUSK Pab in mouse kidney tissue lysates (35ug/lane). MUSK(arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MUSK pTyr755 antibody

Western blot analysis of extracts from JK cells (Lane 2), using MuSK (Phospho-Tyr755) Antibody AP26453PU-N / AP26453PU-S. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

MUSK pTyr755 antibody

Western blot analysis of extracts from JK cells (Lane 2), using MuSK (Phospho-Tyr755) Antibody AP26453PU-N / AP26453PU-S. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

MUSK antibody

MUSK Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK monoclonal antibody (M01), clone 1F3 Western Blot analysis of MUSK expression in Jurkat ( Cat # L017V1 ). Mouse IgG2a 1F3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK monoclonal antibody (M02), clone 4E5 Western Blot analysis of MUSK expression in Jurkat ( Cat # L017V1 ). Mouse IgG2a 4E5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK monoclonal antibody (M03), clone 4C12 Western Blot analysis of MUSK expression in Jurkat ( Cat # L017V1 ). Mouse IgG2a 4C12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MUSK antibody

Immunoperoxidase of monoclonal antibody to MUSK on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml] Mouse IgG2b 2H6 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK Mouse IgG2b 4C4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MUSK antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with MUSK polyclonal antibody ( Cat # PAB3369 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MUSK antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with MUSK polyclonal antibody ( Cat # PAB3370 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK Rabbit Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

MUSK antibody

MUSK Goat Aff - Purified Rt E, WB
0.1 mg / €450.00
  Neuromics Antibodies

MUSK antibody

Western Blot: MUSK Antibody Cat # [NB120-5619] Rabbit IgG Aff - Purified Ms, Rt IP, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

MUSK antibody

Immunohistochemistry: MUSK Antibody (10A4) [NBP1-47441] - Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using anti-MUSK antibody with DAB staining. Mouse IgG1 10A4 Purified Hu C, E, ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

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