MYBPC3 antibody

Principal name

MYBPC3 antibody

Alternative names for MYBPC3 antibody

cardiac-type Myosin-binding protein C, C-protein cardiac muscle isoform

SwissProt ID

O70468 (Mouse), P56741 (Rat), Q14896 (Human), Q90688 (Chick)

Gene ID

4607 (MYBPC3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of MYBPC3 antibody

MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C. It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle. Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. MYBPC3 binds F-Actin, MHC and native thin filaments, and modifies the activity of Actin-activated myosin ATPase. Mutations in the MYBPC3 gene lead mainly to truncation of the protein, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), a heart disorder characterized by ventricular hypertrophy, which often involves the interventricular septum and is usually asymmetric. The MYBPC3 gene maps to chromosome 11p11.2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MYBPC3 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue using MYBPC3 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

MYBPC3 (N-term) antibody

Immunohistochemistry analysis in human heart tissue (Formalin-fixed, Paraffin-embedded) using MYBPC3 antibody Cat.-No. AP52783PU-N (N-term), followed by peroxidase conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MYBPC3 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using MYBPC3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €205.00
  Assay Biotech

MYBPC3 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using MYBPC3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €310.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MYBPC3

MYBPC3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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