MYCN antibody

Principal name

MYCN antibody

Alternative names for MYCN antibody

NMYC, N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37

SwissProt ID

P03966 (Mouse), P04198 (Human), Q63379 (Rat)

Gene ID

4613 (MYCN), 18109 (Mycn)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MYCN antibody

The v-myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans the family consists of five genes: c-myc, N-myc, R-myc, L-myc and B-myc. Amplification of the N-myc gene has been found in human neuroblastomas and cell lines. The extent of N-myc amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-myc gene gives rise to at least two nuclear phosphoproteins of 64 kDa and 67 kDa that exhibit relatively short (30 minute) half lives in vivo and exhibit DNA binding properties in vitro. Members of the Myc gene family code for proteins that homodimerize but do not bind well to DNA. Myc-Max heterodimers, however, bind with great affinity to the sequence CACGTG and act to initiate transcription of target genes.

General readings

Hansford,L.M., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (34), 12664-12669

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  2. Highly Validated (1)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MYCN antibody

Western blot analysis of MYCN over-expressed 293 cell line, cotransfected with MYCN Validated Chimera RNAi ( Cat # H00004613-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MYCN monoclonal antibody (M01), clone 3H4 (Cat # H00004613-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG 3H4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MYCN antibody

WB Suggested Anti-MYCN Antibody Titration: 2.5 ug/ml; Positive Control: Human heart Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MYCN antibody

ELISA: n-Myc Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

MYCN (C-term) antibody

Western blot analysis of MYCN antibody (C-term) (AP17575PU-N) in CEM cell line lysates (35ug/lane). MYCN (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MYCN antibody

MYCN Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MYCN antibody

Western Blot analysis of MYCN expression in transfected 293T cell line (H00004613-T01) by MYCN MaxPab polyclonal antibody.

Lane 1: MYCN transfected lysate(51.04 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

MYCN antibody

MYCN Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

MYCN antibody

Western Blot analysis of MYCN expression in transfected 293T cell line (H00004613-T01) by MYCN MaxPab polyclonal antibody.

Lane 1: MYCN transfected lysate(49.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

MYCN antibody

Detection limit for recombinant GST tagged MYCN is approximately 1ng/ml as a capture antibody. Mouse IgG2b 4H4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MYCN antibody

Human Heart; WB Suggested Anti-MYCN Antibody Titration: 2.5ug/ml. Positive Control: Human heart; MYCN antibody - C-terminal region (ARP32030_T100) in Human Heart cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

MYCN antibody

MYCN Rabbit IgG Aff - Purified Ms P, WB
0.1 ml / €490.00
  Novus Biologicals Inc.

MYCN antibody

MYCN Mouse IgG2a NMYC-1 Purified Hu, Ms IP, WB
0.1 mg / €340.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MYCN

MYCN Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MYCN

MYCN Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

MYCN

MYCN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

MYCN

MYCN Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MYCN 293T Cell Transient Overexpression Lysate(Denatured)

MYCN 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

MYCN overexpression lysate

MYCN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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