Myelin-associated glycoprotein (MAG) antibody

Principal name

Myelin-associated glycoprotein (MAG) antibody

Alternative names for Myelin-associated glycoprotein (MAG) antibody

MAG, GMA, Siglec-4a

SwissProt ID

P07722 (Rat), P20916 (Human), P20917 (Mouse), P22134 (Yeast)

Gene ID

4099 (MAG), 29409 (Mag), 17136

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Goat, Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Myelin-associated glycoprotein (MAG) antibody

MAG(Myelin-associated glycoprotein),also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is thought to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR. MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner. Experiments blocking NgR from interacting with MAG prevented inhibition of neurite outgrowth by MAG. In cultured human embryonic kidney (HEK) cells expressing the NOGO receptor, p75(NTR) was required for MAG-induced intracellular calcium elevation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Myelin-associated glycoprotein (MAG) antibody

  Rabbit Polyclonal Anti-MAG Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (MAG Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Myelin-associated glycoprotein (MAG) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 3C7 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Myelin-associated glycoprotein (MAG) antibody

MAG staining cryostat sections of rat cerebellum (dilution: 25 µg/mL). Tissues were stained using the anti-goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Goat Aff - Purified Rt C, E, ICC/IF, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

MAG - human gene knockout kit via CRISPR

MAG - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MAG - human gene knockout kit via CRISPR

MAG - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAG - human gene knockout kit via CRISPR

MAG - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAG - human gene knockout kit via CRISPR

MAG - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mag - mouse gene knockout kit via CRISPR

Mag - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mag - mouse gene knockout kit via CRISPR

Mag - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mag - mouse gene knockout kit via CRISPR

Mag - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mag - mouse gene knockout kit via CRISPR

Mag - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Myelin-associated glycoprotein (MAG) (transcript variant 1)

  Recombinant protein of human myelin associated glycoprotein (MAG), transcript variant 1  
Myelin-associated glycoprotein (MAG) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Myelin-associated glycoprotein (MAG) (transcript variant 1)

  Purified recombinant protein of Human myelin associated glycoprotein (MAG), transcript variant 1  
Myelin-associated glycoprotein (MAG) Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAG (mGFP-tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAG (mGFP-tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAG (mGFP-tagged)-Human myelin associated glycoprotein (MAG), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAG (mGFP-tagged)-Human myelin associated glycoprotein (MAG), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAG (Myc-DDK tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, MAG (Myc-DDK tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAG (Myc-DDK-tagged)-Human myelin associated glycoprotein (MAG), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAG (Myc-DDK-tagged)-Human myelin associated glycoprotein (MAG), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mag (GFP-tagged) - Mouse myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mag (GFP-tagged) - Mouse myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL  
200 µl / €1,230.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mag (Myc-DDK-tagged) - Mouse myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mag (Myc-DDK-tagged) - Mouse myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mag (GFP-tagged ORF) - Rat myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mag (GFP-tagged ORF) - Rat myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

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