Myelin-associated glycoprotein (MAG) antibody

Principal name

Myelin-associated glycoprotein (MAG) antibody

Alternative names for Myelin-associated glycoprotein (MAG) antibody

MAG, GMA, Siglec-4a

SwissProt ID

P07722 (Rat), P20916 (Human), P20917 (Mouse), P22134 (Yeast)

Gene ID

4099 (MAG), 29409 (Mag), 17136

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Goat, Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Myelin-associated glycoprotein (MAG) antibody

MAG(Myelin-associated glycoprotein),also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is thought to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR. MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner. Experiments blocking NgR from interacting with MAG prevented inhibition of neurite outgrowth by MAG. In cultured human embryonic kidney (HEK) cells expressing the NOGO receptor, p75(NTR) was required for MAG-induced intracellular calcium elevation.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Myelin-associated glycoprotein (MAG) antibody

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (MAG Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Myelin-associated glycoprotein (MAG) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 3C7 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Myelin-associated glycoprotein (MAG) antibody

Western Blot analysis of MAG expression in transfected 293T cell line (H00004099-T01) by MAG MaxPab polyclonal antibody.

Lane 1: MAG transfected lysate(68.86 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Myelin-associated glycoprotein (MAG) antibody

Western Blot analysis of MAG expression in transfected 293T cell line (H00004099-T01) by MAG MaxPab polyclonal antibody.

Lane 1: MAG transfected lysate(68.86 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Myelin-associated glycoprotein (MAG) antibody

MAG monoclonal antibody (M35), clone 3C7. Western Blot analysis of MAG expression in Jurkat(Cat # L017V1 ). Mouse IgG1 3C7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Myelin-associated glycoprotein (MAG) antibody

Myelin-associated glycoprotein (MAG) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Myelin-associated glycoprotein (MAG) antibody

MAG staining cryostat sections of rat cerebellum (dilution: 25 µg/mL). Tissues were stained using the anti-goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Goat Aff - Purified Rt C, E, ICC/IF, WB
0.1 mg / €450.00
  Neuromics Antibodies

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Myelin-associated glycoprotein (MAG) (transcript variant 1)

Myelin-associated glycoprotein (MAG) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Myelin-associated glycoprotein (MAG) (transcript variant 1)

Myelin-associated glycoprotein (MAG) Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Myelin-associated glycoprotein (MAG)

Myelin-associated glycoprotein (MAG) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

Myelin-associated glycoprotein (MAG)

Myelin-associated glycoprotein (MAG) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

Myelin-associated glycoprotein (MAG)

Myelin-associated glycoprotein (MAG) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Myelin-associated glycoprotein (MAG)

Myelin-associated glycoprotein (MAG) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MAG 293T Cell Transient Overexpression Lysate(Denatured)

MAG 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAG (mGFP-tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAG (mGFP-tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAG (Myc-DDK tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, MAG (Myc-DDK tagged) - Human myelin associated glycoprotein (MAG), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mag (GFP-tagged ORF) - Rat myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mag (GFP-tagged ORF) - Rat myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mag (Myc-DDK-tagged ORF) - Rat myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mag (Myc-DDK-tagged ORF) - Rat myelin-associated glycoprotein (Mag), 200 uL, >10^7 TU/mL  
200 µl / €1,152.00
  OriGene Technologies, Inc.

18 Item(s)

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