Myo18A antibody

Principal name

Myo18A antibody

Alternative names for Myo18A antibody

Myosin-XVIIIa, MAJN, KIAA0216, MYSPDZ, Myosin containing a PDZ domain, Molecule associated with JAK3 N-terminus

SwissProt ID

Q92614 (Human), Q9JMH9 (Mouse)

Gene ID

399687 (MYO18A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Myo18A antibody

Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.

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