MYO7A antibody

Principal name

MYO7A antibody

Alternative names for MYO7A antibody

Myosin-VIIa, USH1B

SwissProt ID

P97479 (Mouse), Q13402 (Human), Q28970 (Pig)

Gene ID

4647 (MYO7A)

Available reactivities

Bov (Bovine), GP (Guinea Pig), Hu (Human), Ms (Mouse), Rt (Rat), Av (Birds), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of MYO7A antibody

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

General readings

General / background references:Liu X et al. Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells. Cell Motil Cytoskeleton 37:240-52 (1997). PubMed PMID: 9227854
Hasson T et al. Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B. Proc Natl Acad Sci U S A 92:9815-9 (1995). PubMed PMID: 7568224

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MYO7A (880-1077) antibody

MYO7A Rabbit IgG Aff - Purified Av, Hu, Ms, Por, Rt ICC/IF, WB
50 µg / €340.00
  Acris Antibodies GmbH

MYO7A antibody

MYO7A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MYO7A antibody

Detection limit for recombinant GST tagged MYO7A is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 1D3 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

MYO7A antibody

Western blot analysis of MYO7A expression in SKOVCAR (A); HEK293T (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Por, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

MYO7A antibody

Western blot analysis of MYO7A expression in SKOVCAR (A); HEK293T (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Por, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

MYO7A antibody

Western blot analysis of MYO7A expression in SKOVCAR (A); HEK293T (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Por, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

MYO7A antibody

Western Blot: Myosin VIIa Antibody [NB120-3481] - Figure 1 shows a Western blot of myosin VIIa in mouse testes tissue extract using NB120-3481. Rabbit IgG Aff - Purified Ms WB
0.2 ml / €400.00
  Novus Biologicals Inc.

MYO7A antibody

Immunohistochemistry-Paraffin: Myosin VIIa Antibody [NBP1-84266] Immunohistochemical staining of human adrenal gland shows strong cytoplasmic and membranous positivity in cortical cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MYO7A

MYO7A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

MYO7A

MYO7A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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