Myosin-Va antibody

Principal name

Myosin-Va antibody

Alternative names for Myosin-Va antibody

MYO5A, MYH12, Dilute myosin heavy chain, non-muscle, Myosin heavy chain 12, Myoxin

SwissProt ID

Q02440 (Chick), Q99104 (Mouse), Q9QYF3 (Rat), Q9Y4I1 (Human)

Gene ID

4644 (MYO5A), 17918 (Myo5a)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Myosin-Va antibody

Myosin-Va has been implicated in the regulation of vesicle trafficking in neurons and melanocytes. It has been suggested that class V myosins associate with membrane vesicles through their C-terminal tails. Myosin V associates with synaptic vesicles and forms a stable complex with the synaptic vesicle membrane proteins, synaptobrevin II, and synaptophysin. The dilute Myo5a gene mutation in myosin Va leads to mental retardation, variable cellular immunodeficiency and impaired melanocyte function (pigmentary dilution), known as Griscelli syndrome in humans. Myosin Va regulates melanosome distribution along microfilaments. It is found in association with the centrosome at all stages of the cell cycle. In the interphase stage, myosin Va is found in pericentriolar material. During cell division, it is found in the cytoplasm and concentrates in a trail between migrating centrioles and in the mitotic spindle poles and spindle fibers.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Myosin-Va antibody

  Goat Anti-MYO5A Antibody  
(1ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Myosin-Va antibody

  Rabbit polyclonal anti-MYO5A antibody  
Western blot analysis of extracts from HeLa cells, using MYO5A antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

MYO5A - human gene knockout kit via CRISPR

MYO5A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MYO5A - human gene knockout kit via CRISPR

MYO5A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MYO5A - human gene knockout kit via CRISPR

MYO5A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MYO5A - human gene knockout kit via CRISPR

MYO5A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Myo5a - mouse gene knockout kit via CRISPR

Myo5a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Myo5a - mouse gene knockout kit via CRISPR

Myo5a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Myo5a - mouse gene knockout kit via CRISPR

Myo5a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Myo5a - mouse gene knockout kit via CRISPR

Myo5a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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