Myospryn antibody

Principal name

Myospryn antibody

Alternative names for Myospryn antibody

Dystrobrevin-binding protein 2, Genethonin-3, CMYA5, C5orf10, DTNBP2, SPRYD2, TRIM76, Cardiomyopathy-associated protein 5, SPRY domain-containing protein 2, Tripartite motif-containing protein 76

SwissProt ID

Q70KF4 (Mouse), Q8N3K9 (Human)

Gene ID

202333 (CMYA5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of Myospryn antibody

SPRYD2 Antibody: SPRYD2, also known as Myospryn, was origilly identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Myospryn (C-term) antibody

  Rabbit Polyclonal SPRYD2 Antibody  
Western blot analysis of SPRYD2 in rat brain tissue lysate with SPRYD2 antibody at (A) 1 and (B) 2 ug/mL Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Myospryn antibody

Myospryn Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

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