NAIF1 / C9orf90 antibody

Principal name

NAIF1 / C9orf90 antibody

Alternative names for NAIF1 / C9orf90 antibody

Nuclear apoptosis-inducing factor 1, chromosome 9 open reading frame 90

SwissProt ID

A7MBH3 (Bovin), Q5ZI27 (Chick), Q69YI7 (Human), Q6PFD7 (Mouse)

Gene ID

203245 (NAIF1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of NAIF1 / C9orf90 antibody

NAIF protein 1 (nuclear apoptosis inducing factor 1; CB12-327; RP-379C10.2) belongs to the NAIF1 family. Apoptosis is a genetically determined cell suicidal pro gram that plays critical roles in many physiological and pathological processes. nuclear apoptosis-inducing factor 1 (NAIF1), overexpression of which induces apoptosis in cells. Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. Northern blot analysis revealed wide expression of NAIF1 mRNA throughout human tissues. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.

General readings

Lv B., et al (2006). Int. J. Biochem. Cell Biol. 38:671-683Sinzelle L., et al (2008). Proc. Natl. Acad. Sci. U.S.A. 105:4715-4720

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NAIF1 / C9orf90 antibody

Predicted band size: 35 kDa . Positive control: 293T cell lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 30 ug Primary antibody: 1/750 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NAIF1 / C9orf90 antibody

NAIF1 / C9orf90 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NAIF1 / C9orf90 (1-327, His-tag)

NAIF1 / C9orf90 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

NAIF1 / C9orf90 (1-327, His-tag)

NAIF1 / C9orf90 Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

NAIF1 / C9orf90

NAIF1 / C9orf90 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

C9orf90 293T Cell Transient Overexpression Lysate(Denatured)

C9orf90 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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