NALP12 antibody

Principal name

NALP12 antibody

Alternative names for NALP12 antibody

NLRP12, PYPAF7, RNO, NACHT, LRR and PYD domains-containing protein 12, PYRIN-containing APAF1-like protein 7, Monarch-1, Regulated by nitric oxide

SwissProt ID

E9Q5R7, P59046 (Human)

Gene ID

91662 (NLRP12), 378425

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of NALP12 antibody

May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NALP12 (N-term) antibody

Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP12 antibody

TA326334 (1µg/ml) staining of Mouse Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP12 antibody

TA329088 (1µg/ml) staining of Mouse Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP12 antibody

(LEFT) Western blot analysis of NLRP12 Antibody (AP18136PU-N) in HL-60 cell line lysates (35ug/lane). NLRP12 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of NLRP12 Antibody (AP18136PU-N) in mouse testis tissue lysates (35ug/lane). NLRP12 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

NALP12 control peptide

NALP12
50 µg / €160.00
  Acris Antibodies GmbH

NALP12 antibody

Detection limit for recombinant GST tagged NALP12 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 3B5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NALP12 antibody

Detection limit for recombinant GST tagged NALP12 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 4B9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NALP12 antibody

NALP12 Rabbit Hu C, IP, P
50 µl / €390.00
  Abnova Taiwan Corp.

NALP12 antibody

Western Blot: NALP12 Antibody [NBP1-76293] - Analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

NALP12 antibody

Immunohistochemistry-Paraffin: NALP12 Antibody [NBP1-85555] Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NALP12

NALP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NALP12

NALP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NLRP12 overexpression lysate

NLRP12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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