NALP2 antibody

Principal name

NALP2 antibody

Alternative names for NALP2 antibody

NLRP2, NBS1, PAN1, PYPAF2, NACHT, LRR and PYD domains-containing protein 2

SwissProt ID

Q9NX02 (Human)

Gene ID

55655 (NLRP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NALP2 antibody

NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli (1). Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD) (2). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1Β-processing activity and is thought to function as a modulator of NF-ΚB and procaspase-1 activation in macrophages (2,3). It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs) (4). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.

General readings

1. Ji S, Shin JE, Kim YS, Oh JE, Min BM, Choi Y,
Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells. Infection and immunity 2009 Mar 77 (3): 1044-52.
PMID: 19103770

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NALP2 (C-term) antibody

HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human NLRP2 with DYKDDDDK tag probed with AP20169PU-N (1 µg/ml) in Lane A and probed with anti-DYKDDDDK Tag (1/5000) in Lane C. 
Mock-transfected HEK293 probed with AP20169PU-N  (1 mg/ml) in Lane B. 
Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

NALP2 antibody

Western blot analysis of NALP2 in PC-3 cell lysate with NALP2 antibody at (A) 1 and (B) 2 μg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP2 antibody

HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human NLRP2 with DDK (FLAG) tag probed with TA311469 (1ug/ml) in Lane A and probed with anti-DDK Tag (1:1000) in Lane C. Mock-transfected HEK293 probed with TA311469 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP2 antibody

WB Suggested Anti-NLRP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

NALP2 Control Peptide

NALP2
50 µg / €160.00
  Acris Antibodies GmbH

NALP2 antibody

Western Blot analysis of NLRP2 expression in transfected 293T cell line (H00055655-T01) by NLRP2 MaxPab polyclonal antibody.

Lane 1: NLRP2 transfected lysate(116.82 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

NALP2 antibody

NALP2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

NALP2 antibody

NALP2 Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

NALP2 antibody

NLRP2 MaxPab rabbit polyclonal antibody. Western Blot analysis of NLRP2 expression in mouse spleen. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NALP2 antibody

NALP2 Mouse IgG2a 1B10 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

NALP2 antibody

Western blot analysis of NLRP2 in differentiated THP-1 cells following IFN ( interferon ) g stimulation using NLRP2 polyclonal antibody ( Cat # PAB0267 ) at 1 : 2000. TPA-differentiated THP-1 cells were cultured with 1000 units of IFNg for 0-24 hours as described in Bruey et al, 2004. Culturing differentiated THP-1 with IFNg resulted in transient elevations in NLRP2 expression which peaked at 4-8 h after INFg treatment. Rabbit Hu C, IP, P, WB
50 µl / €390.00
  Abnova Taiwan Corp.

NALP2 antibody

Western blot analysis of NARP2 in PC-3 cell lysate with NLRP2 polyclonal antibody ( Cat # PAB12883 ) at 1 and 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

NALP2 (C-term) antibody

NALP2 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

NALP2 antibody

NALP2 Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €480.00
  Novus Biologicals Inc.

NALP2 antibody

Immunofluorescence: NALP2 Antibody [NBP1-32985] - Immunofluorescence analysis of methanol-fixed HeLa, using NALP2 (NBP1-32985) antibody at 1:200 dilution. Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

NALP2 antibody

NALP2 Goat Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

NALP2 antibody

NALP2 Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

NALP2 antibody

Immunohistochemistry-Paraffin: NALP2 Antibody [NBP1-85553] - Immunohistochemical staining of human gall bladder shows distinct nuclear and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NALP2

NALP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NALP2

NALP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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