NALP2 antibody

Principal name

NALP2 antibody

Alternative names for NALP2 antibody

NLRP2, NBS1, PAN1, PYPAF2, NACHT, LRR and PYD domains-containing protein 2

SwissProt ID

Q9NX02 (Human)

Gene ID

55655 (NLRP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NALP2 antibody

NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli (1). Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD) (2). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1Β-processing activity and is thought to function as a modulator of NF-ΚB and procaspase-1 activation in macrophages (2,3). It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs) (4). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.

General readings

1. Ji S, Shin JE, Kim YS, Oh JE, Min BM, Choi Y,
Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells. Infection and immunity 2009 Mar 77 (3): 1044-52.
PMID: 19103770

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NALP2 (C-term) antibody

HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human NLRP2 with DYKDDDDK tag probed with AP20169PU-N (1 µg/ml) in Lane A and probed with anti-DYKDDDDK Tag (1/5000) in Lane C. 
Mock-transfected HEK293 probed with AP20169PU-N  (1 mg/ml) in Lane B. 
Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

NALP2 antibody

  Rabbit Polyclonal NALP2 Antibody  
Western blot analysis of NALP2 in PC-3 cell lysate with NALP2 antibody at (A) 1 and (B) 2 μg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP2 antibody

  Goat Anti-NLRP2 / NALP2 Antibody  
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human NLRP2 with DDK (FLAG) tag probed with TA311469 (1ug/ml) in Lane A and probed with anti-DDK Tag (1:1000) in Lane C. Mock-transfected HEK293 probed with TA311469 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NALP2 antibody

  Rabbit Polyclonal Anti-NLRP2 Antibody - C-terminal region  
WB Suggested Anti-NLRP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

NALP2 antibody

  Mouse Monoclonal anti-NLRP2 Antibody  
Total cell lysate from A549 cells (lane 1) or A431 cells (lane 2) were resolved by electrophoresis, transferred to nitrocellulose, and probed with purified monoclonal anti-NLRP2 (clone 8F10B51) antibody. Proteins were visualized using an anti-mouse-IgG secondary that was conjugated to HRP and chemiluminescence detection. Mouse 8F10B51 Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NALP2

  Recombinant protein of human NLR family, pyrin domain containing 2 (NLRP2)  
NALP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NLRP2 overexpression lysate

NLRP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NLRP2 (mGFP-tagged) - Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (mGFP-tagged) - Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €2,110.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (mGFP-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €2,110.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (Myc-DDK tagged) - Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (Myc-DDK tagged) - Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,900.00
  OriGene Technologies, Inc.

Lenti ORF particles, NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, NLRP2 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 2 (NLRP2), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €1,900.00
  OriGene Technologies, Inc.

15 Item(s)

per page
  • LinkedIn