NANOS3 antibody

Principal name

NANOS3 antibody

Alternative names for NANOS3 antibody

NOS3, Nanos homolog 3

SwissProt ID

P60323, P60324

Gene ID

342977 (NANOS3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of NANOS3 antibody

Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects. This Nanos3 antibody will not cross-react with either Nanos 1 or Nanos2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NANOS3 (C-term) antibody

NANOS3 Rabbit Purified Hu, Ms, Rt P, WB
  Acris Antibodies GmbH

NANOS3 antibody

NANOS3 Mouse IgG2b 4B11 Hu E, WB
  Abnova Taiwan Corp.

NANOS3 antibody

NANOS3 Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
  Novus Biologicals Inc.


Catalog No.    

NANOS3 overexpression lysate

NANOS3 overexpression lysate  
  OriGene Technologies, Inc.

4 Item(s)

per page
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