Alternative names for NC1.1 antibody
Natural Cytotoxix Cells
Functional assay (FN), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F)
Background of NC1.1 antibody
Recognises an alloantigen designated NC1.1 expressed by murine natural cytotoxic cells. (NC1.1 is a 45kD cell surface antigen). Natural cytotoxic cells represent a small subset of cells with cytotoxic activity against certain tumour cells in functional assays. The IC4 monoclonal antibody has been shown to block substantially NC cells activity in vivo and in vitro. Recognises the NC1.1 alloantigen in CBA, C57BL/6, BALB/c and NZB mice, but not in CE or DBA/2 mice.