NCOR2 / SMRT antibody

Principal name

NCOR2 / SMRT antibody

Alternative names for NCOR2 / SMRT antibody

N-CoR2, TRAC, SMAP270, CTG26, Nuclear receptor corepressor 2, Silencing mediator of retinoic acid and thyroid hormone receptor, Thyroid- retinoic-acid-receptor-associated corepressor, T3 receptor-associating factor

SwissProt ID

Q9WU42 (Mouse), Q9Y618 (Human)

Gene ID

9612 (NCOR2)

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Bov (Bovine), Can (Canine), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ChIP assay (ChIP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), PLA/Proximity ligation assay (PLA)

Background of NCOR2 / SMRT antibody

NCOR2 (Nuclear receptor corepressor 2) is a corepressor that mediates transcriptional repression activity of some nuclear receptors. NCOR2 is a component of a large corepressor complex that contains SIN3A/B and the histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid and retinoic acid receptors (TR and RAR, respectively) in the absence of their ligands. NCOR2 contains two conserved CORNR box motifs, which are essential and sufficient to permit binding to unliganded TR and RAR. Sequences that surround the CORNR box determine specificity for the nuclear receptor. The interaction between NCOR2 and unliganded nuclear receptor is thought to promote the association of these nuclear receptors with TFIIB. NCOR2 is also a component of the N-Cor repressor complex, which also contains NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A, and GPS2.

General readings

General / background references:Hudelist G et al. Expression of sex steroid receptors and their co-factors in normal and malignant breast tissue: AIB1 is a carcinoma-specific co-activator. Breast Cancer Res Treat 78:193-204 (2003). PubMed PMID: 12725419
Thenot S et al. Estrogen receptor cofactors expression in breast and endometrial human cancer cells. Mol Cell Endocrinol 156:85-93 (1999). PubMed PMID: 10612426

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NCOR2 / SMRT antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NCOR2 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

NCOR2 / SMRT antibody

WB Suggested Anti-NCOR2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysateNCOR2 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

NCOR2 / SMRT antibody

WB Suggested Anti-NCOR2 Antibody Titration: 2.5ug/ml; Positive Control: Hela cell lysateNCOR2 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NCOR2 / SMRT antibody

NCOR2 / SMRT Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

NCOR2 / SMRT antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NCOR2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

NCOR2 / SMRT antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NCOR2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

NCOR2 / SMRT antibody

Human HeLa; WB Suggested Anti-NCOR2 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate. NCOR2 is supported by BioGPS gene expression data to be expressed in HeLa.; NCOR2 antibody - N-terminal region (ARP32463_P050) in Human HeLa cells using Western Blot Rabbit IgG Aff - Purified Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

NCOR2 / SMRT antibody

Human HeLa; WB Suggested Anti-NCOR2 Antibody Titration: 2.5ug/ml. Positive Control: Hela cell lysate. NCOR2 is supported by BioGPS gene expression data to be expressed in HeLa.; NCOR2 antibody - N-terminal region (ARP32464_T100) in Human HeLa cells using Western Blot Rabbit IgG Purified Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

NCOR2 / SMRT antibody

Western Blot and Immunoprecipitation: SMRT Antibody [NB100-58826] - Detection of Human SMRT on HeLa whole cell lysate using NB100-58826. SMRT was also immunoprecipitated by rabbit anti-SMRT antibody NB100-58827. Rabbit Aff - Purified Hu IP, PLA, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

NCOR2 / SMRT antibody

NCOR2 / SMRT Mouse IgG1 1542 Purified Hu C, ChIP, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

NCOR2 / SMRT antibody

NCOR2 / SMRT Mouse IgG1 H7 Purified Hu C, ICC/IF, IP, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

NCOR2 / SMRT antibody

Figure 1 illustrates immunolocalization of SMRT in HeLa cells using NB300-568. Mouse IgG1 1212 Ig Fraction Hu ICC/IF, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

NCOR2 / SMRT antibody

NCOR2 / SMRT Rabbit IgG Aff - Purified Hu P
7 ml / €340.00
  Novus Biologicals Inc.

NCOR2 / SMRT antibody

Immunohistochemistry-Paraffin: NCOR2 Antibody [NBP1-85386] - Immunohistochemical staining of human cerebellum shows nuclear positivity in purkinje cells, cells in molecular layer and cells in granular layer. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NCOR2 / SMRT

NCOR2 / SMRT Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NCOR2 / SMRT

NCOR2 / SMRT Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

16 Item(s)

per page
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