NDFIP1 antibody

Principal name

NDFIP1 antibody

Alternative names for NDFIP1 antibody

N4WBP5, PSEC0192, PSEC0223, NEDD4 family-interacting protein 1

SwissProt ID

Q5U2S1 (Rat), Q8R0W6 (Mouse), Q9BT67 (Human)

Gene ID

80762 (NDFIP1), 65113 (Ndfip1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat)

Available hosts

Mouse, Hamster, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of NDFIP1 antibody

NDFIP1 Antibody: The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutiorily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitition by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neurol survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEkt sigling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

General readings

Harvey KF, Shearwin-Whyatt LM, Fotia A, et al. N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. J. Biol. Chem. 2002; 277:9307-17.
Sang Q, Kim MH, Kumar S, et al. Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury. J. Neurosci. 2006; 26:7234-44.
Mund T and Pelham HR. Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2. Proc. Natl. Acad. Sci. USA 2010; 107; 11429-34.
Ramon HE, Beal AM, Liu Y, et al. The E3 ubiquitin ligase adaptor Ndfip1 regulates Th17 differentiation by limiting the production of proinflammatory cytokines. J. Immunol. 2012; epub.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NDFIP1 antibody

Western blot analysis of extracts from 293 cells, using NDFIP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NDFIP1 antibody

Western blot analysis of NDFIP1 in PC-3 cell lysate with NDFIP1 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit Purified Hu, Ms E, WB
0.1 mg / €345.00
  OriGene Technologies, Inc.

NDFIP1 (N-term) antibody

Western blot analysis of NDFIP1 in PC-3 cell lysate with NDFIP1 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDFIP1 (N-term) Control Peptide

NDFIP1
50 µg / €160.00
  Acris Antibodies GmbH

NDFIP1 antibody

Western Blot analysis of NDFIP1 expression in transfected 293T cell line (H00080762-T01) by NDFIP1 MaxPab polyclonal antibody.

Lane 1: NDFIP1 transfected lysate(24.31 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

NDFIP1 antibody

NDFIP1 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

NDFIP1 antibody

NDFIP1 Hamster IgG2b N1Nterm15-32.8 Ms E, WB
0.1 ml / €560.00
  Abnova Taiwan Corp.

NDFIP1 antibody

NDFIP1 Hamster IgG2b N1Nterm1532.8 Purified Ms E, WB
50 µl / €360.00
  Immuquest

NDFIP1 antibody

NDFIP1 Hamster IgG2b N1Nterm1532.8 Purified Ms E, WB
0.1 ml / €400.00
  Immuquest

NDFIP1 antibody

Immunohistochemistry-Paraffin: Ndfip1 Antibody [NBP1-81234] - Immunohistochemical staining of human adrenal gland shows strong cytoplasmic positivity with granular pattern in cortical cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NDFIP1 (1-116, His-tag)

NDFIP1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

NDFIP1 (1-116, His-tag)

NDFIP1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

NDFIP1

NDFIP1 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NDFIP1 293T Cell Transient Overexpression Lysate(Denatured)

NDFIP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

NDFIP1 overexpression lysate

NDFIP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

15 Item(s)

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