NDP antibody

Principal name

NDP antibody

Alternative names for NDP antibody

Norrin, Norrie disease protein,EVR2

SwissProt ID

P48744 (Mouse), Q00604 (Human), Q2KI78 (Bovin)

Gene ID

4693 (NDP)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of NDP antibody

NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. NDP acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). NDP may be involved in a pathway that regulates neural cell differentiation and proliferation. NDP is the genetic locus identified as harboring mutations that result in Norrie disease. Norrie disease is a rare genetic disorder characterized by bilateral congenital blindness that is caused by a vascularized mass behind each lens due to a maldeveloped retina (pseudoglioma). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-94 AL034370.1 53727-53820 c 95-1761 X65882.1 1-1667 1762-1935 BE139596.1 1-174 c

General readings

Luhmann U F., et al. (2005) Invest Pothalmol Vis Sci. 46:3372-3382.Luhmann U F., et al. (2005) Genesis. 42:253-262

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NDP antibody

Western blot analysis of Norrin in Jurkat cell lysate with Norrin antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDP antibody

Western blot analysis of extracts of various cell lines, using NDP antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDP antibody

WB Suggested Anti-NDP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

NDP Control Peptide

NDP
50 µg / €160.00
  Acris Antibodies GmbH

NDP antibody

Western Blot analysis of NDP expression in transfected 293T cell line (H00004693-T02) by NDP MaxPab polyclonal antibody.

Lane 1: NDP transfected lysate(14.63 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

NDP antibody

Human brain; Immunohistochemistry with Brain, cortex tissue at an antibody concentration of 5ug/ml using anti-NDP antibody (ARP56082_P050); NDP antibody - middle region (ARP56082_P050) in Human brain cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

NDP antibody

Western Blot: NDP Antibody [NBP1-59305] - This Anti-NDP antibody was used in Western Blot of Fetal Liver   tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

NDP antibody

Immunocytochemistry: NDP/Norrin   Antibody [NBP1-77014] - Jurkat cells with NDP/Norrin  antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

NDP antibody

Immunohistochemistry-Paraffin: NDP Antibody [NBP1-84769] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in renal tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NDP (25-133, His-tag)

NDP Human Purified > 80 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

NDP (25-133, His-tag)

NDP Human Purified > 80 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

NDP

NDP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

NDP

NDP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

NDP

NDP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NDP

NDP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NDP 293T Cell Transient Overexpression Lysate(Denatured)

NDP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

NDP overexpression lysate

NDP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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