NDRG1 antibody

Principal name

NDRG1 antibody

Alternative names for NDRG1 antibody

CAP43, DRG1, DRG-1, RTP, Rit42, N-myc downstream-regulated gene 1 protein, Nickel-specific induction protein Cap43, Differentiation-related gene 1 protein, Reducing agents and tunicamycin-responsive protein

SwissProt ID

Q3SYX0 (Bovin), Q62433 (Mouse), Q6JE36 (Rat), Q92597 (Human)

Gene ID

10397 (NDRG1), 17988 (Ndrg1)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Rb (Rabbit), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Goat, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C)

Background of NDRG1 antibody

N-myc downstream-regulated gene 1 (NDRG1), also termed Cap43, Drg1, RTP/rit42, and Proxy-1, is a member of the NDRG family, which is composed of four members (NDRG1-4) that function in growth, differentiation, and cell survival. NDRG1 is ubiquitously expressed and highly responsive to a variety of stress sigls including D damage, hypoxia, and elevated levels of nickel and calcium. Expression of NDRG1 is elevated in N-myc defective mice and is negatively regulated by N- and c-myc. During D damage, NDRG1 is induced in a p53-dependent fashion and is necessary for p53-mediated apoptosis. Research studies have shown that NDRG1 may also play a role in cancer progression by promoting differentiation, inhibiting growth, and modulating metastasis and angiogenesis. Nonsense mutation of the NDRG1 gene has been shown to cause hereditary motor and sensory neuropathy-Lom (HMSNL), which is supported by studies demonstrating the role of NDRG1 in maintaining myelin sheaths and axol survival. NDRG1 is up-regulated during mast cell maturation and its deletion leads to attenuated allergic responses. Both NDRG1 and NDRG2 are substrates of SGK1, although the precise physiological role of SGK1-mediated phosphorylation is not known. NDRG1 is phosphorylated by SGK1 at Thr328, Ser330, Thr346, Thr356, and Thr366. Phosphorylation by SGK1 primes NDRG1 for phosphorylation by GSK-3.

General readings

Zhou D et al. Cap43, a novel gene specifically induced by Ni2+ compounds. Cancer Res 58:2182-9 (1998). PubMed: 9605764
Search PubMed (MEDLINE) for references to NDRG1

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NDRG1 antibody

Western blot analysis of extracts of various cell lines, using NDRG1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDRG1 (C-term) antibody

TA302840 staining (0.1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDRG1 antibody

Predicted band size: 43 kDa . Positive control: Human lymphoma tissue lysate. Recommended dilution: 1/500-2000 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NDRG1 antibody

WB Suggested Anti-NDRG1 Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDRG1 antibody

WB Suggested Anti-NDRG1 Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NDRG1 (N-term) antibody

Western blot analysis of NDRG1 Antibody (N-term) (AP17582PU-N) in MDA-MB231 cell line lysates (35ug/lane). NDRG1 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

NDRG1 (C-term) antibody

Immunohistochemistry Image: Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

NDRG1 antibody

NDRG1 Rabbit Serum Ms C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

NDRG1 antibody

NDRG1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

NDRG1 antibody

Immunoperoxidase of monoclonal antibody to NDRG1 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 0.7 ug/ml] Mouse IgG2a 2D7 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NDRG1 antibody

NDRG1 polyclonal antibody ( Cat # PAB6284 ) staining ( 0.1 µg/ml ) of human kidney lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

NDRG1 antibody

Human HepG2; WB Suggested Anti-NDRG1 Antibody Titration: 2.5ug/ml. Positive Control: HepG2 cell lysate; NDRG1 antibody - C-terminal region (ARP47974_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

NDRG1 antibody

Human HepG2; WB Suggested Anti-NDRG1 Antibody Titration: 2.5ug/ml. Positive Control: HepG2 cell lysate; NDRG1 antibody - N-terminal region (ARP47975_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

NDRG1 antibody

NDRG1 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

NDRG1 antibody

Western Blot: NDRG1 Antibody [NB300-839] - NB300-839 staining (1ug/ml) of Human Testis lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

NDRG1 antibody

Western Blot: NDRG1 Antibody [NBP1-32074]-  (30 ug of whole cell lysate) A:NIH-3T3 10% SDS PAGE diluted at 1:1000 Rabbit IgG Hu WB
0.1 ml / €420.00
  Novus Biologicals Inc.

NDRG1 antibody

Immunohistochemistry-Paraffin: NDRG1 Antibody [NBP1-86636] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu, Rt ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

NDRG1 antibody

Immunohistochemistry-Paraffin: NDRG1 Antibody (EPR5593) [NBP1-95851] - Analysis of paraffin-embedded human colon tissue using anti-NDRG1. Rabbit EPR5593 Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

NDRG1 antibody

Immunohistochemistry-Paraffin: NDRG1 Antibody (EPR5592) [NBP1-95976] human colon tissue using anti-NDRG1. Rabbit EPR5592 Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NDRG1 (transcript variant 2)

NDRG1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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