NEB antibody

Principal name

NEB antibody

Alternative names for NEB antibody


SwissProt ID

Q05C45 (Human)

Gene ID

4703 (NEB)

Ncbi ID


Available reactivities

Amph (Amphibian), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Western blot / Immunoblot (WB)

Background of NEB antibody

This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein and its size varies from 600 to 800 kD in a manner that is tissue-, species-,and developmental stage-specific. The 6,669-residue predicted protein, the short form, contains 185 copies of 35-amino acid modules that can be classified into 7 types. It is suggested that alternative splicing may explain the developmental or tissue-specific size variants of nebulin. However, the nucleotide sequence information is not available for other spliced products. Mutations in this gene are associated with recessive nemaline myopathy.

  • LinkedIn