NEB antibody

Principal name

NEB antibody

Alternative names for NEB antibody

Nebulin

SwissProt ID

Q05C45 (Human)

Gene ID

4703 (NEB)

Ncbi ID

NP_004534

Available reactivities

Amph (Amphibian), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse

Available applications

Western blot / Immunoblot (WB)

Background of NEB antibody

This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein and its size varies from 600 to 800 kD in a manner that is tissue-, species-,and developmental stage-specific. The 6,669-residue predicted protein, the short form, contains 185 copies of 35-amino acid modules that can be classified into 7 types. It is suggested that alternative splicing may explain the developmental or tissue-specific size variants of nebulin. However, the nucleotide sequence information is not available for other spliced products. Mutations in this gene are associated with recessive nemaline myopathy.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NEB antibody

NEB Mouse Neb-20 Amph, Chk, Hu, Ms, Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

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