Neisseria meningitidis antibody

Principal name

Neisseria meningitidis antibody

Available reactivities

Bac (Bacteria)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of Neisseria meningitidis antibody

Neisseria meningitidis is a causative agent of bacterial meningitis and resides within the nasopharyngeal tract of humans. Strains of N. meningitidis are characterised by the polysaccharide expressed on its capsule. Serogroups A, B and C cause 90% of meningococcal meningitis cases. The carbohydrate component of the capsular membrane induces a T independent immune response so neither long term immunity by memory cell formation nor antibody affinity maturation is observed. Rather than being engulfed and processed by an antigen presenting cell,the carbohydrate capsule interacts directly with B cells. This interaction causes production of serogroup specific antibodies, primarily IgM. IgG is also produced with an IgG1 response predominating in children and an IgG2 response predominating in adults. The immune systems of infants are not sufficiently developed to achieve an immune response to the polysaccharide membrane which accounts for the prevalence of meningitis in this age group. Persons most susceptible to the infection are often immunocompromised, immunosuppressed or suffering from head trauma. Others acquire infection through close contact with a primary carrier.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neisseria meningitidis (all antigens) antibody

Neisseria meningitidis Rabbit Ig Fraction E, ICC/IF
1 ml / €400.00
  Acris Antibodies GmbH

Neisseria meningitidis (all antigens) antibody

Neisseria meningitidis Rabbit Biotin E, WB
1 ml / €400.00
  Acris Antibodies GmbH

Neisseria meningitidis (all antigens) antibody

Neisseria meningitidis Rabbit FITC ICC/IF
1 ml / €400.00
  Acris Antibodies GmbH

Neisseria meningitidis (all antigens) antibody

Neisseria meningitidis Rabbit HRP C, E
1 ml / €400.00
  Acris Antibodies GmbH

Neisseria meningitidis Orf1/FrpD antibody

Western Blotting analysis ( reducing conditions ) of recombinant protein Orf1/FrpD using polyclonal Orf1/FrpD polyclonal antibody ( Cat # PAB13542 ).
Lane 1, 3, 5 : Cell lysate of Orf1/FrpD-transfected E. coli ; dilution ( 1 ) 0.5 µg/ml, ( 3 ) 0.2 µg/ml, ( 5 ) 0.1 µg/ml; detection with Donkey anti-rabbit / HRP secondary antibody.
Lane 2, 4, 6 : Cell lysates of non-transfected E. coli ( negative controls ). Rabbit IgG Purified WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Neisseria meningitidis antibody

Neisseria meningitidis Rabbit IgG Aff - Purified Bac E, ICC/IF
0.5 ml / €360.00
  Novus Biologicals Inc.

6 Item(s)

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