NELF-B antibody

Principal name

NELF-B antibody

Alternative names for NELF-B antibody

Negative elongation factor B, COBRA1, KIAA1182, NELFB, Cofactor of BRCA1

SwissProt ID

Q8C4Y3 (Mouse), Q8WX92 (Human)

Gene ID

25920 (COBRA1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), EPair for Elisa (EPair), Enzyme Immunoassay (E)

Background of NELF-B antibody

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis (Zhong H et al., 2004).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NELF-B antibody

Immunoperoxidase of purified MaxPab antibody to COBRA1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), ICC/IF, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

NELF-B antibody

Western blot of neonatal rat brain lysate showing specific immunolabeling Mouse IgG1 F7E4 Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NELF-B (Center) antibody

COBRA1 Antibody (Center) (Cat. #AP14765c) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the COBRA1 antibody detected the COBRA1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

NELF-B antibody

Western Blot analysis of COBRA1 expression in transfected 293T cell line (H00025920-T02) by COBRA1 MaxPab polyclonal antibody.

Lane 1: RP13-122B23.3 transfected lysate(53.90 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NELF-B antibody

Immunohistochemistry-Paraffin: COBRA1 Antibody [NBP1-05977] - human breast carcinoma.  NBP1-05977 a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte PlusTM  555 a dilution of 1:100. Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

NELF-B antibody

Immunohistochemistry-Paraffin: COBRA1 Antibody [NBP1-82924] - Immunohistochemical staining of human small intestine shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NELF-B

NELF-B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NELF-B

NELF-B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

NELF-B

NELF-B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

COBRA1 (Human) Matched Antibody Pair

COBRA1 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

COBRA1 293T Cell Transient Overexpression Lysate(Denatured)

COBRA1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

NELFB overexpression lysate

NELFB overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

12 Item(s)

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