Nephrocystin 1 antibody

Principal name

Nephrocystin 1 antibody

Alternative names for Nephrocystin 1 antibody

NPHP1, NPH1

SwissProt ID

O15259 (Human), O15259-4, Q9QY53 (Mouse), Q9TU19 (Canfa)

Gene ID

4867 (NPHP1), 53885 (Nphp1)

Available reactivities

Ms (Mouse), Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Nephrocystin 1 antibody

Together with Cas NPHP1 may play a role in the control of epithelial cell polarity. NPHP1 seems to help to recruit protein tyrosine kise 2 beta (PTK2B) to cell matrix adhesions, thereby initiating phosphorylation of PTK2B and PTK2B-dependent sigling.This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion sigling, likely as part of a multifunctiol complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neotal breathing abnormalities, sometimes including retil dystrophy and rel disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Nephrocystin 1 antibody

WB Suggested Anti-NPHP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

Nephrocystin 1 antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Ms WB
0.25 mg / €370.00
  Acris Antibodies GmbH

Nephrocystin 1 antibody

Western Blot analysis of NPHP1 expression in transfected 293T cell line (H00004867-T01) by NPHP1 MaxPab polyclonal antibody.

Lane 1: NPHP1 transfected lysate(13.31 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Nephrocystin 1 antibody

Nephrocystin 1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Nephrocystin 1 antibody

NPHP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NPHP1 expression in A-431. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Nephrocystin 1 antibody

NPHP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of NPHP1 expression in mouse testis. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Nephrocystin 1 antibody

Western blot of Nephrophthisis (pic) polyclonal antibody ( Cat # PAB10408 ) used at 2?V10 µg/ml and for Immunoprecipitation 10-20 µg/ml. Rabbit IgG Purified Ms IP, WB
0.25 mg / €400.00
  Abnova Taiwan Corp.

Nephrocystin 1 antibody

Human Heart; WB Suggested Anti-NPHP1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human heart; NPHP1 antibody - middle region (ARP56084_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Nephrocystin 1 antibody

Western blot analysis of Nephrocystin 1 expression in HeLa (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Nephrocystin 1 antibody

Western blot analysis of Nephrocystin 1 expression in HeLa (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Nephrocystin 1 antibody

Western blot analysis of Nephrocystin 1 expression in HeLa (A); Raw264.7 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

Nphp1 - mouse gene knockout kit via CRISPR

Nphp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Nphp1 - mouse gene knockout kit via CRISPR

Nphp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nphp1 - mouse gene knockout kit via CRISPR

Nphp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Nephrocystin 1

Nephrocystin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Nephrocystin 1

Nephrocystin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Nephrocystin 1

Nephrocystin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Nephrocystin 1

Nephrocystin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

NPHP1 (Human) IP-WB Antibody Pair

NPHP1 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

NPHP1 (Human) Matched Antibody Pair

NPHP1 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

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