Neurabin-2 antibody

Principal name

Neurabin-2 antibody

Alternative names for Neurabin-2 antibody

PPP1R9B, PPP1R6, Neurabin-II, Spinophilin, Protein phosphatase 1 regulatory subunit 9B

SwissProt ID

O35274 (Rat), Q6R891 (Mouse), Q96SB3 (Human)

Gene ID

84687 (PPP1R9B), 84686 (Ppp1r9b)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P)

Background of Neurabin-2 antibody

Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity). Required for hepatocyte growth factor (HGF)-induced cell migration.

General readings

Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010).
Rajagopal, S., et al. J. Biol. Chem. 285(23):18060-18071 (2010).
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163 (2009).
Sagara, M., et al. Oncogene 28(10):1357-1365 (2009).
Meng, X., et al. Eur. J. Immunol. 39(2):552-560 (2009).

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurabin-2 (N-term) antibody

Western blot analysis of Neurabin-2 Antibody (N-term) Cat.-No AP53419PU-N in Ramos cell line lysates (35ug/lane). This demonstrates the PPP1R9B antibody detected the PPP1R9B protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Neurabin-2 antibody

Neurabin-2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


Neurabin-2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.


Neurabin-2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.


Neurabin-2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

5 Item(s)

per page
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