Neuregulin 1 antibody

Principal name

Neuregulin 1 antibody

Alternative names for Neuregulin 1 antibody

NRG1, GGF, HGL, HRGA, NDF, SMDF, Heregulin, HRG, Breast cancer cell differentiation factor p45, Glial growth factor, Neu differentiation factor, Pro-neuregulin-1 membrane-bound isoform, Acetylcholine receptor-inducing activity, Sensory and motor neuron-derived factor

SwissProt ID

O93383 (Xenla), P43322 (Rat), Q02297 (Human), Q05199 (Chick), Q9UPE3 (Human)

Gene ID

3084 (NRG1), 112400 (Nrg1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), Mky (Monkey), Eq (Equine), Por (Porcine), Sh (Sheep), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP)

Background of Neuregulin 1 antibody

Neuregulin 1 (NRG1) interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues.Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentialtion of epithelial, neuronal, glial, and other types of cells.

General readings

1. Choi W  et al. The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin. J Cell Sci 123:3102-11 (2010). IHC-Fr, WB ; Human . PubMed: 20736300

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuregulin 1 antibody

  Rabbit polyclonal NRG1 isoform-10 antibody  
Western blot analysis of extracts from SKOV3 cells, using NRG1 isoform-10 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Neuregulin 1 antibody

  Biotinylated Anti-Human Heregulinß-1 Rabbit Polyclonal Antibody  
To detect Human Heregulin-beta1 by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant Human Heregulin-beta1. Rabbit IgG Purified Hu E, WB
50 µg / €335.00
  OriGene Technologies, Inc.

Neuregulin 1 antibody

  Anti-Human Heregulinß-1 Rabbit Polyclonal Antibody  
To detect Human Heregulin-beta1 by sandwich ELISA (using 100ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human Heregulin-beta1(TA328336) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human Heregulin-beta1. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Neuregulin 1 antibody

  Rabbit Polyclonal Anti-NRG1 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse brain tissue, A172 cells, Primary antibody: (NRG1 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Neuregulin 1 antibody

  Rabbit Polyclonal Anti-NRG1 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hela cells, A549 cells, Primary antibody: (NRG1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes Rabbit IgG Purified Hu E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Neuregulin 1 antibody

Immunohistochemistry (IHC) analysis of Neuregulin-1/SMDF antibody (Cat.-No.: AP06168PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

Neuregulin 1 (Isoform 10) (N-term) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
50 µl / €380.00
  OriGene Technologies GmbH

Neuregulin 1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NRG1 isoform-10 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Neuregulin 1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NRG1 isoform-10 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

9 Item(s)

per page
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