Neuregulin 3 antibody

Principal name

Neuregulin 3 antibody

Alternative names for Neuregulin 3 antibody

NRG3, Pro-NRG3, Pro-neuregulin-3, membrane-bound isoform

SwissProt ID

P56975 (Human), P56975-4

Gene ID

10718 (NRG3)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Can (Canine), Chk (Chicken), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of Neuregulin 3 antibody

NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization. There are 4 different isoforms.

General readings

Hijazi MM, Young PE, Dougherty MK, Bressette DS, Cao TT, Pierce JH, Wong LM, Alimandi M, King CR. NRG-3 in human breast cancers: activation of multiple erbB family proteins. Int J Oncol. 1998 Nov;13(5):1061-7. PMID: 9772300

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuregulin 3 antibody

TA303129 (0.3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neuregulin 3 antibody

WB Suggested Anti-NRG3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Neuregulin 3 (694-708) antibody

Adrenal Medulla: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

Neuregulin 3 antibody

NRG3 polyclonal antibody ( Cat # PAB7582 ) ( 0.3 µg/ml ) staining of human brain ( cerebellum ) lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Neuregulin 3 antibody

Human brain; Brain, cortex; NRG3 antibody - middle region (ARP44588_P050) in Human brain cells using Immunohistochemistry Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Neuregulin 3 antibody

Neuregulin 3 Goat Aff - Purified Ms C, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

6 Item(s)

per page
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