Neuregulin 3 antibody

Principal name

Neuregulin 3 antibody

Alternative names for Neuregulin 3 antibody

NRG3, Pro-NRG3, Pro-neuregulin-3, membrane-bound isoform

SwissProt ID

P56975 (Human), P56975-4

Gene ID

10718 (NRG3)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Chk (Chicken), Can (Canine), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Neuregulin 3 antibody

NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization. There are 4 different isoforms.

General readings

Uhl,G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuregulin 3 antibody

  Goat Polyclonal Antibody against NRG3  
TA303129 (0.3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neuregulin 3 antibody

  Rabbit Polyclonal Anti-NRG3 Antibody  
WB Suggested Anti-NRG3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Neuregulin 3 antibody

  Rabbit Polyclonal Anti-NRG3 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal brain tissue, Primary antibody: (NRG3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Neuregulin 3 (694-708) antibody

Adrenal Medulla: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

Neuregulin 3 antibody

Neuregulin 3 Goat Aff - Purified Ms C, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

NRG3 - human gene knockout kit via CRISPR

NRG3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NRG3 - human gene knockout kit via CRISPR

NRG3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NRG3 - human gene knockout kit via CRISPR

NRG3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NRG3 - human gene knockout kit via CRISPR

NRG3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NRG3 (mGFP-tagged)-Human neuregulin 3 (NRG3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRG3 (mGFP-tagged)-Human neuregulin 3 (NRG3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRG3 (mGFP-tagged)-Human neuregulin 3 (NRG3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRG3 (mGFP-tagged)-Human neuregulin 3 (NRG3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRG3 (mGFP-tagged) - Human neuregulin 3 (NRG3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRG3 (mGFP-tagged) - Human neuregulin 3 (NRG3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRG3 (Myc-DDK-tagged)-Human neuregulin 3 (NRG3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRG3 (Myc-DDK-tagged)-Human neuregulin 3 (NRG3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRG3 (Myc-DDK-tagged)-Human neuregulin 3 (NRG3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, NRG3 (Myc-DDK-tagged)-Human neuregulin 3 (NRG3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, NRG3 (Myc-DDK tagged) - Human neuregulin 3 (NRG3), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, NRG3 (Myc-DDK tagged) - Human neuregulin 3 (NRG3), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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