Neurofibromin antibody

Principal name

Neurofibromin antibody

Alternative names for Neurofibromin antibody

NF1,NF-1

SwissProt ID

P21359 (Human), P35608 (Chick), P97526 (Rat), Q04690 (Mouse)

Gene ID

4763 (NF1)

Available reactivities

Hu (Human), GP (Guinea Pig), Ms (Mouse), Rt (Rat), Fi (Fish), Bov (Bovine), Chk (Chicken), Can (Canine), Mky (Monkey), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot)

Background of Neurofibromin antibody

Neurofibromatosis type 1 (NF1), or von Reckinghausen neurofibromatosis, is one of the most common autosomal dominant disorders in humans. Early linkage analysis mapped the NF1 gene to chromosome 17. The predicted NF1 transcript encodes a 2818 amino acid protein designated NF1GRP. By sequence analysis, similarity has been demonstrated within a small region of NF1GRP and members of the Ras GAP gene family. Functionally, NF1GRP was shown by biochemical analysis involving RAS-GAP hydrolysis and functional complementation in yeast to further resemble GAP protein. The NF1 protein is expressed at relatively constant levels in a broad range of cell lines and tissues including brain, lung, liver, kidney, spleen, muscle and colon. Although little is known regarding the function of NF1GRP, the homology with the catalytic domain of proteins with GTPase activity suggests that the NF1GRP may also interact in vivo with Ras proteins.

General readings

FEBS Lett. 2001 Apr 6;494(1-2):48-53.
Phosphorylation of neurofibromin by cAMP-dependent protein kinase is regulated via a cellular association of N(G),N(G)-dimethylarginine dimethylaminohydrolase.
Tokuo H, Yunoue S, Feng L, Kimoto M, Tsuji H, Ono T, Saya H, Araki N.
Department of Tumor Genetics and Biology, Kumamoto University School of Medicine, Japan.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurofibromin antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Neurofibromin antibody

Immunohistochemistry: Neurofibromin Antibody (McNFn27b) - Immunohistochemical staining of adult human dorsal root ganglia, using anti-McNFn27b. Mouse IgG1 McNFn27b Purified GP, Hu, Ms, Rt C, E, IP
0.2 ml / €325.00
  OriGene Technologies, Inc.

Neurofibromin antibody

Western blot analysis of extracts from HepG2 cells, using NF1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Neurofibromin antibody

Western Blot: Neurofibromin 1 Antibody [TA336613] - Western Blot of (A, B, C above). Rabbit Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.5 ml / €325.00
  OriGene Technologies, Inc.

Neurofibromin antibody

ELISA: Neurofibromin 1 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neurofibromin antibody

Western blot (WB) analysis of Neurofibromin antibody (Cat.-No.: AP01247PU-N) in extracts from HepG2 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Neurofibromin antibody

Neurofibromin Rabbit IgG Liquid Chk, Ms, Rt C, P, WB
0.2 ml / €340.00
  Acris Antibodies GmbH

Neurofibromin antibody

Neurofibromin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Neurofibromin antibody

Detection limit for recombinant GST tagged NF1 is approximately 3ng/ml as a capture antibody. Mouse IgG 2D1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Neurofibromin antibody

Western blot analysis of NF1 in Schwann cells from embryonic knockout mice, adult human nerves and neonatal rat nerves with NF1 monoclonal antibody, clone McNFn27a ( Cat# MAB2305 ). Mouse IgG1 McNFn27a GP, Hu, Ms, Rt E, IP, WB
0.2 ml / €470.00
  Abnova Taiwan Corp.

Neurofibromin antibody

Immunohistochemical staining of NF1 on human dorsal root ganglia with NF1 monoclonal antibody, clone McNFn27 ( Cat# MAB2306 ). Mouse IgG1 McNFn27 GP, Hu, Ms, Rt C, E, IP
0.2 ml / €470.00
  Abnova Taiwan Corp.

Neurofibromin antibody

Neurofibromin Rabbit Hu, Ms, Rt C, P, WB
0.5 ml / €470.00
  Abnova Taiwan Corp.

Neurofibromin antibody

The tissue lysates derived from hypoxic mouse brain were immunoblotted by NF1 polyclonal antibody ( Cat # PAB12636 ) at 1 : 1000. Rabbit Bov, Hu, Ms, Rt Dot, E, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Neurofibromin antibody

The tissue lysates derived from hypoxic mouse brain were immunoblotted by NF1 ( phospho S2741 ) polyclonal antibody ( Cat # PAB12637 ) at 1 : 1000. Rabbit Bov, Hu, Ms, Rt Dot, E, IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Neurofibromin antibody

The tissue lysates derived from hypoxic mouse brain were immunoblotted by NF1 polyclonal antibody ( Cat # PAB12717 ) at 1 : 1000. Rabbit Bov, Hu, Ms, Rt E, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Neurofibromin antibody

Immunofluorescence analysis of HepG2 cells, using NF1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

Neurofibromin antibody

Immunofluorescence analysis of HepG2 cells, using NF1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

Neurofibromin antibody

Immunohistochemical analysis of NF1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Por, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Neurofibromin antibody

Immunohistochemical analysis of NF1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Por, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Neurofibromin antibody

Immunohistochemical analysis of NF1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Por, Rt ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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