Alternative names for Neurogenin-3 antibody
NGN-3, NGN3, NEUROG3, ATOH5, BHLHA7, Class A basic helix-loop-helix protein 7, Protein atonal homolog 5
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))
Background of Neurogenin-3 antibody
Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.