Neuroligin-2 antibody

Principal name

Neuroligin-2 antibody

Alternative names for Neuroligin-2 antibody

NLGN2, KIAA1366

SwissProt ID

Q62888 (Rat), Q69ZK9 (Mouse), Q8NFZ4 (Human)

Gene ID

57555 (NLGN2), 117096 (Nlgn2)

Available reactivities

Hu (Human), Rt (Rat), Can (Canine), Ms (Mouse)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Neuroligin-2 antibody

Neuroligins (NLGNs) are family of postsyptic cell adhesion molecules that play an important role in syptic development and function. Four genes encode for the different members of the neuroligin family in mammals: NLGN 1-4, which are differentially enriched in postsyptic specializations of sypses. Neuroligin 2 (NLGN2) is expressed in neurons in the brain and also in pancreatic Ã? cells where it facilitates insulin secretion.Syptic maturation is promoted by the binding of Neuroligin 2 with presyptic Neurexins, and these interactions are restricted to particular combitions of isoforms of the binding partners. NLGN2 plays a role in sypse function and syptic sigl transmission, especially via ?-aminobutyric acid receptors (GABA(A) receptors). NLGN2 modulates sigling by inhibitory sypses, and thereby plays a role in controlling the ratio of sigling by excitatory and inhibitory sypses and information processing. Recent studied identified a loss-of-function mutation of NLGN2 in schizophrenia patients, suggesting an indispensable role of NLGN2 in regulating GABAergic functions5.

General readings

1. Zelano J, Berg A, Thams S, Hailer NP, Cullheim S.
SynCAM1 expression correlates with restoration of central synapses on spinal motoneurons after two different models of peripheral nerve injury. J Comp Neurol. 2009 Dec 10;517(5):670-82. PMID: 19827159

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuroligin-2 antibody

TA303198 (0.1µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neuroligin-2 antibody

Western blot analysis of rat brain membrane (lanes 1 and 4), mouse brain membrane (lanes 2 and 5) and rat PC-12 cells (lanes 3 and 6): 1-3. Anti-Neuroligin 2 (extracellular) antibody , (1:400). 4-6. Anti-Neuroligin 2 (extracellular) antibody preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Neuroligin-2 antibody

Western blot analysis of NLGN2 in rat brain tissue lysate with NLGN2 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neuroligin-2 antibody

NLGN2 polyclonal antibody ( Cat # PAB7584 ) ( 0.1 µg/ml ) staining of human pancreas lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Neuroligin-2 antibody

NBP1-00220 (0.1ug/ml) staining of Human Pancreas lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

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