Neuronal acetylcholine receptor subunit beta-3 antibody

Principal name

Neuronal acetylcholine receptor subunit beta-3 antibody

Alternative names for Neuronal acetylcholine receptor subunit beta-3 antibody

Nicotinic acetylcholine receptor subunit beta 3, CHRNB3

SwissProt ID

P12391 (Rat), P43679 (Chick), Q05901 (Human), Q8BMN3 (Mouse)

Gene ID

1142 (CHRNB3)

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Xen (Xenopus)

Available hosts

Rabbit, Goat, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Neuronal acetylcholine receptor subunit beta-3 antibody

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer\'s and Parkinson\'s diseases. nAChRs also play a significant role in nicotine addiction.

General readings

Zeiger J, Haberstick BC, Schlaepfer I, Collins AC, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Lessem J, McQueen MB, Rhee SH, Ehringer MA.
The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco.
Hum Mol Genet. 2007 Nov 30
PMID: 18055561

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuronal acetylcholine receptor subunit beta-3 antibody

  Goat Polyclonal Antibody against CHRNB3  
TA303358 (1µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neuronal acetylcholine receptor subunit beta-3 antibody

  Rabbit Polyclonal Anti-CHRNB3 Antibody  
WB Suggested Anti-CHRNB3 Antibody Titration: 0.03ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

CHRNB3 - human gene knockout kit via CRISPR

CHRNB3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CHRNB3 - human gene knockout kit via CRISPR

CHRNB3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CHRNB3 - human gene knockout kit via CRISPR

CHRNB3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CHRNB3 - human gene knockout kit via CRISPR

CHRNB3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chrnb3 - mouse gene knockout kit via CRISPR

Chrnb3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Chrnb3 - mouse gene knockout kit via CRISPR

Chrnb3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chrnb3 - mouse gene knockout kit via CRISPR

Chrnb3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chrnb3 - mouse gene knockout kit via CRISPR

Chrnb3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CHRNB3 overexpression lysate

CHRNB3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Chrnb3 (GFP-tagged) - Mouse cholinergic receptor, nicotinic, beta polypeptide 3 (Chrnb3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Chrnb3 (GFP-tagged) - Mouse cholinergic receptor, nicotinic, beta polypeptide 3 (Chrnb3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Chrnb3 (Myc-DDK-tagged) - Mouse cholinergic receptor, nicotinic, beta polypeptide 3 (Chrnb3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Chrnb3 (Myc-DDK-tagged) - Mouse cholinergic receptor, nicotinic, beta polypeptide 3 (Chrnb3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Chrnb3 (GFP-tagged ORF) - Rat cholinergic receptor, nicotinic, beta 3 (Chrnb3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Chrnb3 (GFP-tagged ORF) - Rat cholinergic receptor, nicotinic, beta 3 (Chrnb3), 200 uL, >10^7 TU/mL  
200 µl / €1,070.00
  OriGene Technologies, Inc.

Lenti ORF particles, Chrnb3 (Myc-DDK-tagged ORF) - Rat cholinergic receptor, nicotinic, beta 3 (Chrnb3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Chrnb3 (Myc-DDK-tagged ORF) - Rat cholinergic receptor, nicotinic, beta 3 (Chrnb3), 200 uL, >10^7 TU/mL  
200 µl / €958.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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