Neuronal acetylcholine receptor subunit beta-4 antibody

Principal name

Neuronal acetylcholine receptor subunit beta-4 antibody

Alternative names for Neuronal acetylcholine receptor subunit beta-4 antibody

Nicotinic acetylcholine receptor subunit beta 4, CHRNB4

SwissProt ID

P12392 (Rat), P26153 (Chick), P30926 (Human), Q8R493 (Mouse), Q8SPU6 (Bovin)

Gene ID

1143 (CHRNB4), 25103 (Chrnb4)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Neuronal acetylcholine receptor subunit beta-4 antibody

Acetylcholine, released by cholinergic neurons, activates two groups of acetylcholine receptors (AChRs); muscarinic AChRs (mAChRs) which belong to the superfamily of G-protein coupled receptors (GPCRs) and nicotinic AChRs (ChRs) which belong to the ligand-gated ion channel superfamily. ChRs also respond to nicotine, hence their me.To date, 17 different but related subunits of ChRs have been identified and cloned. They consist of a subunits (a1-10), which are responsible for the binding of ligands. In fact, this subunit includes a Cys-loop in the first extracellular domain that is required for agonist binding. The other subunits responsible for making up the active receptor are the Ã? (Ã?1-4), ?, d and e subunits3. Structurally, all subunits have the following: a conserved large extracellular N-termil domain, 3 conserved transmembrane domains, a variable cytoplasmic loop and a fourth transmembrane domain with a short extracellular C-termil domain. An active ChR is generally a heteropentamer of these various subunits organized around a central pore.While most Ã? subunits are neurol, the Ã?1 subunit forms functiol receptors along with other subunits in the muscle. In neurons the a2-a6 and Ã?2-Ã?4 subunits form heteropentameric receptors, usually with a (ax)2(Ã?y)3 stoichiometry.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuronal acetylcholine receptor subunit beta-4 antibody

Western blot analysis of SH-SY5Y human neuroblastoma cell lysate (lanes 1 and 4), rat dorsal root ganglion (lanes 2 and 5) and mouse brain (lanes 3 and 6) lysates: 1-3. Anti-Nicotinic Acetylcholine Receptor ß4(extracellular) antibody, (1:200). 4-6. Anti-Nicotinic Acetylcholine Receptor ß4 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Neuronal acetylcholine receptor subunit beta-4 antibody

Neuronal acetylcholine receptor subunit beta-4 Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Neuronal acetylcholine receptor subunit beta-4 antibody

Neuronal acetylcholine receptor subunit beta-4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Neuronal acetylcholine receptor subunit beta-4 antibody

Neuronal acetylcholine receptor subunit beta-4 Goat Bov, Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Neuronal acetylcholine receptor subunit beta-4 antibody

Neuronal acetylcholine receptor subunit beta-4 Rabbit Serum Hu P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Neuronal acetylcholine receptor subunit beta-4

Neuronal acetylcholine receptor subunit beta-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Neuronal acetylcholine receptor subunit beta-4

Neuronal acetylcholine receptor subunit beta-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CHRNB4 overexpression lysate

CHRNB4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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