Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to Acris Antibodies Inc. (North America)
Home » Target » Neuroserpin / SERPINI1 antibody

Neuroserpin / SERPINI1 antibody

(reset)

Principal name

Neuroserpin / SERPINI1 antibody

Alternative names for Neuroserpin / SERPINI1 antibody

Serpin I1, PI12, PI-12, Peptidase inhibitor 12

SwissProt ID

O35684 (Mouse), Q90935 (Chick), Q99574 (Human), Q9JLD2 (Rat)

Gene ID

5274 (SERPINI1), 20713 (Serpini1), 116459

Ncbi ID

9606, NP_001116224.1, NP_005016, NP_001116224, NM_009250, NM_053779, NM_005025, NM_001122752

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chimp (Chimpanzee), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Neuroserpin / SERPINI1 antibody

Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala. The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB).

General readings

Onda M, Belorgey D, Sharp LK, Lomas DA. Latent Ser49Pro neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies. J Biol Chem. 2005 Jan 21

H00005274-M01 - Neuroserpin / SERPINI1
Immunoperoxidase of monoclonal antibody to SERPINI1 on formalin-fixed paraffin-embedded human cerebral cortex. [antibody concentration 3 ug/ml]
H00005274-M01 - Neuroserpin / SERPINI1
SERPINI1 monoclonal antibody (M01), clone 1D10 Western Blot analysis of SERPINI1 expression in HeLa ( Cat # L013V1 ).
H00005274-M01 - Neuroserpin / SERPINI1
Detection limit for recombinant GST tagged SERPINI1 is approximately 0.3ng/ml as a capture antibody.
PAB6763 - Neuroserpin / SERPINI1
SERPINI1 polyclonal antibody ( Cat # PAB6763 ) ( 1 µg/ml ) staining of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence.
H00005274-M03 - Neuroserpin / SERPINI1
SERPINI1 monoclonal antibody (M03), clone 1E10. Western Blot analysis of SERPINI1 expression in HeLa ( Cat # L013V1 ).
AP01329PU-N - Neuroserpin / SERPINI1
Western blot (WB) analysis of Neuropsin antibody (Cat.-No.: AP01329PU-N) in extracts from Jurkat cells.
ARP56616_P050 - Neuroserpin / SERPINI1
Human NCI-H226; WB Suggested Anti-SERPINI1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: NCI-H226 cell lysate; SERPINI1 antibody - middle region (ARP56616_P050) in Human NCI-H226 cells using Western Blot
AM31816PU-N - Neuroserpin / SERPINI1
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
AM31816PU-N - Neuroserpin / SERPINI1
SERPINI1 monoclonal antibody AM31816PU-N, Western Blot analysis of SERPINI1 expression in HeLa.
AM31816PU-N - Neuroserpin / SERPINI1
Detection limit for recombinant GST tagged SERPINI1 is approximately 0.3ng/ml as a capture antibody.
AP53865PU-N - Neuroserpin / SERPINI1
Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SERPINI1 antibody (N-term) Cat.-No AP53865PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SERPINI1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
AP53865PU-N - Neuroserpin / SERPINI1
Confocal Immunofluorescent analysis of SERPINI1 Antibody (N-term)Cat.-No AP53865PU-N with HepG2 cell followed by Alexa Fluor® 488-conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
AP53865PU-N - Neuroserpin / SERPINI1
Western blot analysis using SERPINI1 Antibody (N-term) Cat.-No AP53865PU-N in HepG2 cell line lysates (35ug/lane). This demonstrates the SERPINI1 antibody detected the SERPINI1 protein (arrow).
TP723330 - Neuroserpin / SERPINI1
TA303009 - Neuroserpin / SERPINI1
TA303009 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA323794 - Neuroserpin / SERPINI1
Predicted band size: 46 kDa . Positive control: Mouse brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA328402 - Neuroserpin / SERPINI1
To detect Human Neuroserpin by direct ELISA (using 100 ml/well) a concentration of approximately 1.0 ug/ml of this antibody is required. This biotinylated polyclonal antibody allows the detection of at least 0.2-0.4 ng/well of recombinant Human Neuroserpin.
TA328403 - Neuroserpin / SERPINI1
To detect hNeuroserpin by sandwich ELISA (using 100ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human Neuroserpin (TA328402) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hNeuroserpin.
TA328403 - Neuroserpin / SERPINI1
To detect hNeuroserpin by sandwich ELISA (using 100ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human Neuroserpin (TA328402) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hNeuroserpin.
TA342233 - Neuroserpin / SERPINI1
WB Suggested Anti-SERPINI1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: NCI-H226 cell lysate
TA347830 - Neuroserpin / SERPINI1
Western blot analysis of extract from Mouse brain tissue using Neuroserpin Antibody

Items 1 to 20 of 22 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neuroserpin / SERPINI1 antibody
  Goat Polyclonal Antibody against SERPINI1  
TA303009 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Chimp, Hu, Ms, Rt WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Neuroserpin / SERPINI1 antibody
  Anti-SERPINI1 Rabbit Polyclonal Antibody  
Predicted band size: 46 kDa . Positive control: Mouse brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Neuroserpin / SERPINI1 antibody
  Biotinylated Anti-Human Neuroserpin Rabbit Polyclonal Antibody  
To detect Human Neuroserpin by direct ELISA (using 100 ml/well) a concentration of approximately 1.0 ug/ml of this antibody is required. This biotinylated polyclonal antibody allows the detection of at least 0.2-0.4 ng/well of recombinant Human Neuroserpin. Rabbit IgG Purified Hu E, WB
50 µg / €335.00
  OriGene Technologies, Inc.

Neuroserpin / SERPINI1 antibody
  Anti-Human Neuroserpin Rabbit Polyclonal Antibody  
To detect hNeuroserpin by sandwich ELISA (using 100ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human Neuroserpin (TA328402) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hNeuroserpin. Rabbit IgG Purified Hu E, WB
0.1 mg / €335.00
  OriGene Technologies, Inc.
+1 additional image

Neuroserpin / SERPINI1 antibody
  Rabbit polyclonal Anti-SERPINI1 Antibody  
WB Suggested Anti-SERPINI1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: NCI-H226 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Ze WB
50 µg / €360.00
  OriGene Technologies, Inc.

Neuroserpin / SERPINI1 antibody
  Rabbit Polyclonal Anti-Neuroserpin Antibody  
Western blot analysis of extract from Mouse brain tissue using Neuroserpin Antibody Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

Neuroserpin / SERPINI1 antibody
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1D10 Purified Hu E, P, WB
50 µg / €420.00
  Acris Antibodies GmbH
+2 additional images

Neuroserpin / SERPINI1 antibody
Western blot (WB) analysis of Neuropsin antibody (Cat.-No.: AP01329PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Neuroserpin / SERPINI1 (N-term) antibody
Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SERPINI1 antibody (N-term) Cat.-No AP53865PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SERPINI1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH
+2 additional images

CRISPR

Catalog No. Species Donor Vector  

SERPINI1 - human gene knockout kit via CRISPR
SERPINI1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SERPINI1 - human gene knockout kit via CRISPR
SERPINI1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SERPINI1 - human gene knockout kit via CRISPR
SERPINI1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SERPINI1 - human gene knockout kit via CRISPR
SERPINI1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Neuroserpin / SERPINI1 (transcript variant 1)
  Purified recombinant protein of Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1.  
Neuroserpin / SERPINI1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
25 µg / €139.00
  OriGene Technologies, Inc.
 

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SERPINI1 (mGFP-tagged) - Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, SERPINI1 (mGFP-tagged) - Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, SERPINI1 (mGFP-tagged)-Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, SERPINI1 (mGFP-tagged)-Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, SERPINI1 (Myc-DDK tagged) - Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1 , 200 uL, >10^7 TU/mL
Lenti ORF particles, SERPINI1 (Myc-DDK tagged) - Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €969.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, SERPINI1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, SERPINI1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €969.00
  OriGene Technologies, Inc.
 

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Serpini1 (GFP-tagged) - Mouse serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Serpini1 (GFP-tagged) - Mouse serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1), 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Serpini1 (Myc-DDK-tagged) - Mouse serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Serpini1 (Myc-DDK-tagged) - Mouse serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1), 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.
 

Items 1 to 20 of 22 total

per page
Page:
  1. 1
  2. 2
22 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (4)
  2. Human Lenti ORF Particle (4)
  3. Mouse Lenti ORF Particle (2)
  4. Primary Antibody (9)
  5. Protein | Growth Factor (1)
  6. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (8)
  2. Monoclonal (1)
Target
  1. Neuroserpin / SERPINI1 (10)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (9)
  2. Mouse (Ms) (5)
  3. Rat (Rt) (3)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
  6. Chimpanzee (Chimp) (1)
  7. Equine (Eq) (1)
  8. Rabbit (Rb) (1)
  9. Zebrafish (Ze) (1)
Applications
  1. Western blot / Immunoblot (WB) (8)
  2. Enzyme Immunoassay (E) (3)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. Paraffin Sections (P) (2)
Presentation
  1. Purified (6)
  2. Aff - Purified (3)
Host
  1. Rabbit (7)
  2. Goat (1)
  3. Mouse (1)
Images
  1. 1 image (10)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (8)
  2. Paraffin Sections (P) (2)
  3. ELISA (capture) (E(capture)) (1)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Species (Protein)
  1. Human (1)
Source
  1. E. coli (1)
Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. Acris - OriGene (22)
Service
  • OriGene EU
  • Acris Antibodies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info@acris-online.de
  • orders: ordering@acris-online.de
 
© Copyright 1998 - 2017 Acris Antibodies GmbH
  • LinkedIn