Neuroserpin / SERPINI1 antibody
Principal name
Neuroserpin / SERPINI1 antibody
Alternative names for Neuroserpin / SERPINI1 antibody
Serpin I1, PI12, PI-12, Peptidase inhibitor 12
Ncbi ID
9606, NP_001116224.1, NP_005016, NP_001116224, NM_009250, NM_053779, NM_005025, NM_001122752
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of Neuroserpin / SERPINI1 antibody
Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala. The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB).
General readings
Onda M, Belorgey D, Sharp LK, Lomas DA. Latent Ser49Pro neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies. J Biol Chem. 2005 Jan 21

















Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA303009 | Neuroserpin / SERPINI1 antibody |
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Goat Polyclonal Antibody against SERPINI1 | |||||||
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Goat | Aff - Purified | Chimp, Hu, Ms, Rt | WB |
0.1 mg /
€360.00
|
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OriGene Technologies, Inc. | |||||||
TA323794 | Neuroserpin / SERPINI1 antibody |
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Anti-SERPINI1 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA328402 | Neuroserpin / SERPINI1 antibody |
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Biotinylated Anti-Human Neuroserpin Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
50 µg /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA328403 | Neuroserpin / SERPINI1 antibody |
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Anti-Human Neuroserpin Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 mg /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
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TA342233 | Neuroserpin / SERPINI1 antibody |
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Rabbit polyclonal Anti-SERPINI1 Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, Hu, Ms, Rb, Ze | WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
TA347830 | Neuroserpin / SERPINI1 antibody |
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Rabbit Polyclonal Anti-Neuroserpin Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
||
OriGene Technologies, Inc. | |||||||
AM31816PU-N | Neuroserpin / SERPINI1 antibody |
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Mouse | IgG1 | 1D10 | Purified | Hu | E, P, WB |
50 µg /
€420.00
|
Acris Antibodies GmbH | |||||||
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AP01329PU-N | Neuroserpin / SERPINI1 antibody |
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Rabbit | Aff - Purified | Hu, Ms | ICC/IF, WB |
0.1 mg /
€350.00
|
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Acris Antibodies GmbH | |||||||
AP53865PU-N | Neuroserpin / SERPINI1 (N-term) antibody |
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Rabbit | Ig | Aff - Purified | Hu | ICC/IF, P, WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
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CRISPR
Catalog No. | Species | Donor Vector | |
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KN205290 | SERPINI1 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN205290BN | SERPINI1 - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN205290LP | SERPINI1 - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN205290RB | SERPINI1 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
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TP723330 | Neuroserpin / SERPINI1 (transcript variant 1) |
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Purified recombinant protein of Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1. | |||||
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Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
25 µg /
€139.00
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OriGene Technologies, Inc. | |||||
Human Lenti ORF Particles
Catalog No. | ||
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RC205290L2V | Lenti ORF particles, SERPINI1 (mGFP-tagged) - Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€1,082.00
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OriGene Technologies, Inc. | ||
RC225640L2V | Lenti ORF particles, SERPINI1 (mGFP-tagged)-Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 2, 200 uL, >10^7 TU/mL |
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200 µl /
€1,082.00
|
|
OriGene Technologies, Inc. | ||
RC205290L1V | Lenti ORF particles, SERPINI1 (Myc-DDK tagged) - Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 1 , 200 uL, >10^7 TU/mL |
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200 µl /
€969.00
|
|
OriGene Technologies, Inc. | ||
RC225640L1V | Lenti ORF particles, SERPINI1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade I (neuroserpin), member 1 (SERPINI1), transcript variant 2, 200 uL, >10^7 TU/mL |
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200 µl /
€969.00
|
|
OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
Catalog No. | ||
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MR206454L2V | Lenti ORF particles, Serpini1 (GFP-tagged) - Mouse serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1), 200 uL, >10^7 TU/mL |
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200 µl /
€907.00
|
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OriGene Technologies, Inc. | ||
MR206454L1V | Lenti ORF particles, Serpini1 (Myc-DDK-tagged) - Mouse serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1), 200 uL, >10^7 TU/mL |
|
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200 µl /
€804.00
|
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OriGene Technologies, Inc. | ||