Neurotensin receptor 3 antibody

Principal name

Neurotensin receptor 3 antibody

Alternative names for Neurotensin receptor 3 antibody

Sortilin, Glycoprotein 95, 100 kDa NT receptor, SORT1, NTR3, Gp95

SwissProt ID

O54861 (Rat), Q6PHU5 (Mouse), Q99523 (Human)

Gene ID

6272 (SORT1), 20661 (Sort1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse, Sheep

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Neutralisation (NEUT), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Neurotensin receptor 3 antibody

FUNCTION: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi. SUBUNIT: Interacts with the cytosolic adapter proteins GGA1 and GGA2. Interacts with numerous ligands including the receptor-associated protein LRPAP1/RAP and GM2A, LPL, PSAP and SLC2A4. Forms a complex with NGFR which binds specifically to the precursor form of NGFB (proNGFB). Interacts with the precursor form of BDNF (proBDNF). SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. Note: Localized to membranes of the endosomes, Golgi stack, lysosomes and nucleus. Localization to the plasma membrane in adipocytes is enhanced by insulin. Localized to the endoplasmic reticulum and the plasma membrane. Also found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes. TISSUE SPECIFICITY: Highly expressed in fat, brain, and lung. Expressed in neuronal bodies and dendrites of the piriform cortex and hippocampus. Also expressed in the islands of Calleja, medial and lateral septal nuclei, amygdaloid nuclei, thalamic nuclei, the supraoptic nucleus, the substantia nigra, the Purkinje layer of the cerebellar cortex and the cranial motor nerve nuclei of the brainstem.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurotensin receptor 3 antibody

Immunohistochemistry: Sortilin Antibody [NB100-91285] - IHC on rat brain (cortex) using Rabbit antibody to extracellular, c-terminal part of Sortilin (Neurotensin receptor 3, NTR3, Sort1): whole serum NB100-91285 at 1 : 1000 dilution. Rabbit Serum Ms, Rt P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Neurotensin receptor 3 antibody

Immunofluorescence: Sortilin Antibody [NB100-98771] - IF (triple labeling, confocal) on rat trigeminal at 1 : 500 dilution using Rabbit antibody to Transforming protein RhoA (Arha, Arha2): whole serum  in red, Sheep antibody to extracellular, N-terminal part of Sortilin (Neurotensin receptor 3, NTR3, Sort1): whole serum  in green, DAPI counterstained appearing in blue. Sheep Serum Ms, Rt P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Neurotensin receptor 3 antibody

Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain lysate: 1, 2. Anti-Sortilin (extracellular) antibody , (1:400). 3, 4. Anti-Sortilin (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Mouse IgG2a 1B3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 antibody

IHC on rat trigeminal nerve ( free floating cryo section ) using rabbit SORT1 polyclonal antibody ( Cat # PAB0734 ) at a dilution of 1 : 1000. Rabbit Hu, Ms, Rt C, E
0.1 ml / €390.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 (Extracell. Dom.) antibody

Sortilin staining of immersion fixed paraffin-embedded sections of human brain using Human at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB  (brown) and counterstained with hematoxylin (blue). Goat IgG Aff - Purified Hu E, NEUT, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

Neurotensin receptor 3 (Extracell. Dom.) antibody

Sortilin staining of immersion fixed paraffin-embedded sections of mouse brain using Human at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB  (brown) and counterstained with hematoxylin (blue). Goat IgG Aff - Purified Ms E, NEUT, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

Neurotensin receptor 3 antibody

Immunohistochemistry-Paraffin: Sortilin Antibody [NBP1-89745] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Neurotensin receptor 3

Neurotensin receptor 3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Neurotensin receptor 3

Neurotensin receptor 3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 (Carrier Free)

Neurotensin receptor 3 Human Purified > 97 % Mouse
50 µg / €400.00
  Neuromics Antibodies

13 Item(s)

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