Neurotensin receptor 3 antibody

Principal name

Neurotensin receptor 3 antibody

Alternative names for Neurotensin receptor 3 antibody

Sortilin, Glycoprotein 95, 100 kDa NT receptor, SORT1, NTR3, Gp95

SwissProt ID

O54861 (Rat), Q6PHU5 (Mouse), Q99523 (Human)

Gene ID

6272 (SORT1), 20661 (Sort1), 83576

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Neutralisation (NEUT), Paraffin Sections (P)

Background of Neurotensin receptor 3 antibody

Sortilin is a member of the Vps10p family med for a yeast gene that is involved in trafficking between the trans-golgi network and the vacuole. In mammals sortilin has been shown to play an important role in golgi to endosome and golgi to lysosome trafficking. Sortilin is also known as neurotensin receptor 3 (NTS3), one of the receptors for the peptide neurotransmitter neurotensin that exerts several biological functions ranging from the regulation of dopamine transmission and pain in the central nervous system to its functioning as a local hormone affecting the gastrointestil tract. In addition, sortilin has been lately identified as a co-receptor of p75NTR for the binding of the proneurotrophins proNGF and proBDNF. Moreover, Sortilin expression was found to be essential for proNGF and proBDNF-induced neurol cell death.Sortilin is a type I membrane protein with a large extracellular domain that includes 8 bacterial neuraminidase repeats (BNRs), a single transmembrane region and a short cytoplasmic tail. The protein is expressed in several tissues, most notably in brain, spil chord, skeletal muscle and adipocytes.Paradoxically for its role as either a neurotensin receptor or a p75NTR co-receptor for proneurotrophins, about 90% of sortilin is retained in intracellular compartments with only about 10% reaching the cell surface. It has been speculated, that changes in the cellular environment may increase cell surface expression of sortilin.We have now developed a new anti-Sortilin antibody directed at the extracellular region of the human sortilin protein. The antibody will recognize human rat and mouse samples.

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurotensin receptor 3 antibody

Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain lysate: 1, 2. Anti-Sortilin (extracellular) antibody , (1:400). 3, 4. Anti-Sortilin (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 antibody

Neurotensin receptor 3 Mouse IgG2a 1B3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 antibody

IHC on rat trigeminal nerve ( free floating cryo section ) using rabbit SORT1 polyclonal antibody ( Cat # PAB0734 ) at a dilution of 1 : 1000. Rabbit Hu, Ms, Rt C, E
0.1 ml / €390.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 (Extracell. Dom.) antibody

Sortilin staining of immersion fixed paraffin-embedded sections of human brain using Human at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB  (brown) and counterstained with hematoxylin (blue). Goat IgG Aff - Purified Hu E, NEUT, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

Neurotensin receptor 3 (Extracell. Dom.) antibody

Sortilin staining of immersion fixed paraffin-embedded sections of mouse brain using Human at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB  (brown) and counterstained with hematoxylin (blue). Goat IgG Aff - Purified Ms E, NEUT, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Neurotensin receptor 3

Neurotensin receptor 3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Neurotensin receptor 3

Neurotensin receptor 3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Neurotensin receptor 3 (Carrier Free)

Neurotensin receptor 3 Human Purified > 97 % Mouse
50 µg / €400.00
  Neuromics Antibodies

Lysates (Knockout)

Catalog No.    

SORT1-knockout Cell lysate

SORT1-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Sort1 (GFP-tagged ORF) - Rat sortilin 1 (Sort1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Sort1 (GFP-tagged ORF) - Rat sortilin 1 (Sort1), 200 uL, >10^7 TU/mL  
200 µl / €1,550.00
  OriGene Technologies, Inc.

Lenti ORF particles, Sort1 (Myc-DDK-tagged ORF) - Rat sortilin 1 (Sort1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Sort1 (Myc-DDK-tagged ORF) - Rat sortilin 1 (Sort1), 200 uL, >10^7 TU/mL  
200 µl / €1,391.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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