Neurotrophin 4 / NTF4 antibody

Principal name

Neurotrophin 4 / NTF4 antibody

Alternative names for Neurotrophin 4 / NTF4 antibody

Neurotrophin-4, NT-4, Neutrophic factor 4, Neurotrophin 5, Neurotrophin-5, NTF5, NT-5

SwissProt ID

P24727 (Xenla), P34130 (Human), P34131 (Rat), Q80VU4 (Mouse)

Gene ID

4909 (NTF4), 78405 (Ntf5), 25730 (Ntf4)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit, Sheep

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Functional assay (FN), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of Neurotrophin 4 / NTF4 antibody

The neurotrophins ("neuro" means nerve and "trophe" means nutrient) are a family of soluble, basic growth factors which regulate neurol development, maintence, survival and death in the CNS and the PNS. Neurotrophin-4 (NT-4) is expressed in neurons of the superior cervical, stellate and celiac ganglion, T-cells and is synthesized by keratinocytes. The structural hallmark of all the neurotrophins is the characteristic arrangement of the disulfide bridges known as the cysteine knot, which has been found in other growth factors such as PDGF. The rat and human forms of NT-4 are 96% homologous. NT-4 has been shown to promote dendritic outgrowth and calcium currents in cultured mesencephalic dopamine neurons, to promote growth and remodeling of adult motor neuron innervation, to be anterograde survival factors for postsyptic cells and to protect against apoptotic neurol death. The biological effects of NT-4 are mediated by two receptors: TrkB, which is specific for NT-4 and BDNF, and p75 which binds all the neurotrophins.

General readings

Nalbandian A, Pang AL, Rennert OM, Chan WY, Ravindranath N, Djakiew D.
A novel function of differentiation revealed by cDNA microarray profiling of p75NTRregulated gene expression.
Differentiation. 2005 Oct;73(8):385-96.
PMID: 16316409

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurotrophin 4 / NTF4 antibody

  NT4 (Neurotrophin 4) mouse monoclonal antibody, clone OTI2E8 (formerly 2E8)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-NTF4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500034) Mouse IgG1 OTI2E8 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Neurotrophin 4 / NTF4 antibody

  Goat Anti-Neurotrophin 5 / NT4 Antibody  
TA305753 (0.1ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neurotrophin 4 / NTF4 antibody

  Anti-NTF4 Rabbit Polyclonal Antibody  
Predicted band size: 22 kDa . Positive control: 231 cell lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Neurotrophin 4 / NTF4 antibody

  Rabbit Polyclonal Anti-NT4  
Western blot analysis of hNT-4, (10 ng): 1. Anti-NT-4 antibody, (1:200). 2. Anti-NT-4, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Neurotrophin 4 / NTF4 antibody

  Rabbit Polyclonal Anti-NTF5 Antibody - N-terminal region  
WB Suggested Anti-NTF5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

Neurotrophin 4 / NTF4 antibody

  NT4 (Neurotrophin 4) mouse monoclonal antibody, clone OTI4D2 (formerly 4D2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NTF4 (RC204535, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NTF4. Mouse IgG1 OTI4D2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Neurotrophin 4 / NTF4 antibody

Neurotrophin 4 / NTF4 Mouse IgG2a Azide Free Hu E
0.5 mg / €220.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4 antibody

Neurotrophin 4 / NTF4 Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4 antibody

Neurotrophin 4 / NTF4 Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4 antibody

Neurotrophin 4 / NTF4 Rabbit Aff - Purified Hu C, E, FN, WB
50 µg / €220.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4 antibody

Neurotrophin 4 / NTF4 Rabbit Aff - Purified Hu C, E, FN, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4 antibody

Neurotrophin-4 (NT-4) staining paraffin-embedded human brain (cortex). Intense staining is seen in cortical neurons Goat Aff - Purified Hu C, E, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

NTF4 - human gene knockout kit via CRISPR

NTF4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NTF4 - human gene knockout kit via CRISPR

NTF4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NTF4 - human gene knockout kit via CRISPR

NTF4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NTF4 - human gene knockout kit via CRISPR

NTF4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Neurotrophin 4 / NTF4

  Purified recombinant protein of Human neurotrophin 4 (NTF4).  
Neurotrophin 4 / NTF4 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 10 µg / €199.00

Special Price: 10 µg / €139.00

  OriGene Technologies, Inc.

Neurotrophin 4 / NTF4 (81-210)

Neurotrophin 4 / NTF4 Human Purified > 85 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4 (81-210)

Neurotrophin 4 / NTF4 Human Purified > 85 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Neurotrophin 4 / NTF4

Neurotrophin 4 / NTF4 Human > 98 % E. coli
2 µg / €140.00
  Acris Antibodies GmbH

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