Neurturin antibody

Principal name

Neurturin antibody

Alternative names for Neurturin antibody

NRTN

SwissProt ID

P97463 (Mouse), Q99748 (Human)

Gene ID

4902 (NRTN), 18188 (Nrtn)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Sheep, Mouse

Available applications

Enzyme Immunoassay (E), Functional assay (FN), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Neutralisation (NEUT)

Background of Neurturin antibody

Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin (1, 2). Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha (3,4). The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently (3-8) and termed GDNFRbeta, Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently (9). NTN binds to and forms a complex with GFRalpha-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.

General readings

Ye M, Wang XJ, Zhang YH, Lu GQ, Liang L, Xu JY, Chen SD.
Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease.
Brain Res. 2007 Apr 20;1142:206-16. Epub 2006 Dec 24.
PMID: 17336273

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurturin (C-term) antibody

TA303262 (0.1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neurturin (C-term) antibody

TA303263 (0.1µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neurturin antibody

Western blot analysis of NTN in HeLa cell lyaste containing 10 or 2.5 ng of full length recombinant NTN with neurturin antibody at 1:500. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Neurturin antibody

Predicted cell location: Cytoplasm. Positive control: Human ovarian and breast cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using NRTN antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Neurturin antibody

Predicted cell location: Cytoplasm. Positive control: Human ovarian and cervical cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using NRTN antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Neurturin antibody

Western-Blot detection of human NRTN expressed in CHO cells. Lane 1: hNRTN-containing CHOEBNALT85 cell culture supernatant. Lane 2: Negative control - CHOEBNALT85 cell culturesupernatant. 5 µl of supernatant were loaded per line. Primary antibody dilution 1:5000 was used. AP-conjugated Goat-anti mouse, was used as secondary antibody. Antibody recognizes protein dimeric, and monomeric variants. Mouse IgG1 3D12 Aff - Purified Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Neurturin antibody

Western-Blot detection of human NRTN expressed in CHO cells. Lane 1: hNRTN-containing CHOEBNALT85 cell culture supernatant. Lane 2: Negative control - CHOEBNALT85 cell culturesupernatant. 5 µl of supernatant were loaded per line. Primary antibody dilution 1:5000 was used. AP-conjugated Goat-anti mouse, was used as secondary antibody. Antibody recognizes protein dimeric, and monomeric variants. Mouse IgG1 4G8 Aff - Purified Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Neurturin antibody

Western-Blot detection of human NRTN expressed in CHO cells. Lane 1: hNRTN-containing CHOEBNALT85 cell culture supernatant. Lane 2: Negative control - CHOEBNALT85 cell culturesupernatant. 5 µl of supernatant were loaded per line. Primary antibody dilution 1:5000 was used. AP-conjugated Goat-anti mouse, was used as secondary antibody. Antibody recognizes protein dimeric, and monomeric variants. Mouse IgG1 1B11 Aff - Purified Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Neurturin antibody

Western blot analysis using neuturin antibody on HeLa cell lysate containing 10 (1) and 2.5 (2) ng of full length recombinant neuturin. Rabbit IgG Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Neurturin Control Peptide

Neurturin
50 µg / €160.00
  Acris Antibodies GmbH

Neurturin antibody

Western-Blot detection of human NRTN expressed in CHO cells. Lane 1: hNRTN-containing CHOEBNALT85 cell culture supernatant. Lane 2: Negative control - CHOEBNALT85 cell culturesupernatant. 5 µl of supernatant were loaded per line. Primary antibody dilution 1:5000 was used. Rb pAb to Chk IgY was used as secondary antibody. Antibody recognizes protein dimeric, and monomeric variants. Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Neurturin antibody

Neurturin Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Neurturin antibody

Neurturin Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Neurturin antibody

Neurturin Rabbit Aff - Purified Hu E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

Neurturin antibody

Neurturin Rabbit Aff - Purified Hu E, FN, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Neurturin antibody

NRTN polyclonal antibody ( Cat # PAB7328 ) ( 0.1 µg/ml ) staining of human heart lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Neurturin antibody

The Nrtn polyclonal antibody ( Cat # PAB7329 ) ( 0.1 µg/ml ) staining of mouse brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Neurturin antibody

Western blot analysis using NRTN polyclonal antibody ( Cat # PAB10138 ) on HeLa cell lysate containing 10 ng of full length recombinant NRTN. Hu, Ms, Rt
0.1 mg / €470.00
  Abnova Taiwan Corp.

Neurturin antibody

Neurturin Sheep Hu, Ms, Rt C, E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Neurturin antibody

NB100-68153 (0.1µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

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