NFATC2 antibody

Principal name

NFATC2 antibody

Alternative names for NFATC2 antibody

NFATC2, NFAT-1, NFATP, Nuclear factor of activated T-cells, cytoplasmic 2,T-cell transcription factor NFAT1, NFAT pre-existing subunit

SwissProt ID

Q13469 (Human), Q60591 (Mouse)

Gene ID

4773 (NFATC2), 18019 (Nfatc2)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Dot blot (Dot), Paraffin Sections (P)

Background of NFATC2 antibody

NFATC2(Nuclear factor of activated T-cells, cytoplasmic 2),also known as NFATP or the 'preexisting component' of NFAT, is present in the cytosolic fraction of unstimulated T cells, which is also a member of the nuclear factor of activated T cells (NFAT) family. The NFATC2 gene is mapped on 20q13.2. NFATC2 is highly homologous to NFATC1 over a limited domain which shows similarity to the Dorsal/Rel family but has a wider tissue distribution. Ectopic expression of NFATC2 inhibited the basal activity of the human CDK4 promoter. Additionally, both Calna-/- and Nfatc2 -/- mice had elevated protein levels of Cdk4, confirming a negative regulatory role for the calcineurin/NFAT pathway. NFATC2 controls myoblast fusion at a specific stage of myogenesis after the initial formation of a myotube and is necessary for further cell growth. Overexpression of NFATC2 promoted differentiation of osteoclast precursor cells into tartrate-resistant acid phosphatase-positive (TRAP-positive) multinucleated osteoclast-like cells even in the absence of RANKL

General readings

Celil Aydemir AB, Lee S, Won Kim D, Gardner TR, Prince D, Mok Ahn J, Young-In Lee F, Nuclear factor of activated T cell mediates proinflammatory gene expression in response
to mechanotransduction. Ann. N. Y. Acad. Sci. 2007 Nov 1117 : 138-42.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NFATC2 antibody

  Goat Anti-NFATC2 / NFAT1 Antibody  
TA305927 (0.3ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFATC2 antibody

  Anti-NFATC2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm or Nucleus. Positive control: Human thyroid and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using NFATC2 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

NFATC2 antibody

  Anti-NFATC2 Rabbit Polyclonal Antibody  
Predicted band size: 98 kDa . Positive control: Human fetal brain tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/650 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NFATC2 antibody

  NFATC2 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of mouse fetal brain cell line, using NFATC2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFATC2 antibody

  Rabbit Polyclonal Anti-NFATC2 Antibody  
WB Suggested Anti-NFATC2 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFATC2 antibody

  Rabbit Polyclonal Anti-NFATC2 Antibody  
WB Suggested Anti-NFATC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

NFATC2 antibody

  Mouse Monoclonal anti-NFATc2 Antibody  
Total cell lysates from Raji cells (lane 1) and mouse splenocytes (lane 2) were resolved by electrophoresis, transferred to nitrocellulose, and probed with purified monoclonal anti-NFATC2 (clone 16A12A31) antibody. Proteins were visualized using an anti-mouse-IgG secondary conjugated to HRP and chemiluminescence detection. Mouse 16A12A31 Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFATC2 pSer330 antibody

Dot blot analysis of anti-NFATC2-pSer330 Phospho-specific Pab (Cat.#AP12851PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Rabbit Ig Aff - Purified Hu
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

NFATC2 - human gene knockout kit via CRISPR

NFATC2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

NFATC2 - human gene knockout kit via CRISPR

NFATC2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

NFATC2 - human gene knockout kit via CRISPR

NFATC2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

NFATC2 - human gene knockout kit via CRISPR

NFATC2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nfatc2 - mouse gene knockout kit via CRISPR

Nfatc2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Nfatc2 - mouse gene knockout kit via CRISPR

Nfatc2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nfatc2 - mouse gene knockout kit via CRISPR

Nfatc2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nfatc2 - mouse gene knockout kit via CRISPR

Nfatc2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NFATC2 (transcript variant 2)

  Recombinant protein of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 2  
NFATC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NFATC2 (transcript variant 1)

  Recombinant protein of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 1  
NFATC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

NFATC2 (transcript variant D)

  Purified recombinant protein of Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant D  
NFATC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NFATC2 overexpression lysate

NFATC2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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