NFKBIB / IKBB antibody

Principal name

NFKBIB / IKBB antibody

Alternative names for NFKBIB / IKBB antibody

I-kappa-B-beta, TRIP9, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9, NF-kappa-B inhibitor beta, Thyroid receptor-interacting protein 9

SwissProt ID

Q15653 (Human), Q60778 (Mouse), Q9JIA3 (Rat)

Gene ID

4793 (NFKBIB)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine), GP (Guinea Pig), Rb (Rabbit), Ye (Yeast)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of NFKBIB / IKBB antibody

Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis. NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which ictivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kises (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitition pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds D at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-766 BM449613.1 1-766 767-1189 BU634404.1 18-440 c 1190-1198 AI684894.1 1-9 c

General readings

Shirane, M. et al. (1999) J Biol Chem 274, 28169-28174.
DiDonato J, et al. (1996) Mol Cell Biol 16(4): 1295-304

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NFKBIB / IKBB antibody

NFKBIB / IKBB Rabbit Serum Hu, Ms, Rt E, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

Western blot analysis of IkappaB-beta expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

Western blot analysis of extracts of various cell lines, using NFKBIB antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

WB Suggested Anti-NFKBIB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate. NFKBIB is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

Lanes: ; Lane 1: 100ug mouse liver lysate; Lane 2: 100ug mouse brain lysate; Lane 3: 100ug mouse heart lysate; Lane 4: 100ug mouse kidney lysate; Lane 5: 100ug mouse lung lysate; Lane 6: 100ug mouse thymus lysate; Lane 7: 100ug mouse spleen lysate; Lane 8: 100ug mouse testis lysate; Lane 9: 100ug HeLa cell lysate; Primary Antibody Dilution: ; 1:1000; Secondary Antibody: ; Anti-rabbit-AP; Secondary Antibody Dilution: ; 1:10,000; Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

WB Suggested Anti-NFKBIB Antibody Titration: 5.0 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysateNFKBIB is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

WB Suggested Anti-NFKBIB Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, GP, Hu, Ms, Rb, Rt, Ye WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NFKBIB / IKBB antibody

Western blot analysis using NFKBIB antibody Cat.-No AM06491SU-N against Jurkat (1) cell lysate. Mouse IgG1 7B4 Ascites Hu E, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

NFKBIB / IKBB pSer23 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using IκB-β antibody (AP02536PU-S; AP02536PU-N). Rabbit Aff - Purified Hu P
0.1 ml / €320.00
  Acris Antibodies GmbH

NFKBIB / IKBB pSer23 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using IκB-β antibody (AP02536PU-S; AP02536PU-N). Rabbit Aff - Purified Hu P
50 µl / €240.00
  Acris Antibodies GmbH

NFKBIB / IKBB antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Small intestine, Peyer's patch. Rabbit Hu E, ICC/IF, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

NFKBIB / IKBB antibody

Western blot (WB) analysis of IkB-β antibody (Cat.-No.: AP21089PU-N) at 1/500 dilution Lane1:Hela whole cell lysate treated with H2O2 Lane2:HEK293T whole cell lysate treated with LPS Lane3:Mouse liver tissue lysate Lane4:Mouse kidney tissue lysate Lane5:Rat kidney tissuelysate Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

NFKBIB / IKBB control peptide

NFKBIB / IKBB Purified
50 µg / €190.00
  Acris Antibodies GmbH

NFKBIB / IKBB antibody

Immunoperoxidase of purified MaxPab antibody to NFKBIB on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml] Mouse Serum Hu E(detection), ICC/IF, P, WB
50 µl / €370.00
  Abnova Taiwan Corp.

NFKBIB / IKBB antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between NFKBIB and FBXW11. HeLa cells were stained with anti-NFKBIB rabbit purified polyclonal 1:1200 and anti-FBXW11 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NFKBIB / IKBB antibody

Immunoperoxidase of monoclonal antibody to NFKBIB on formalin-fixed paraffin-embedded human lung. [antibody concentration 5 ug/ml] Mouse IgG2a 1B5 Purified Hu E, P
0.1 mg / €370.00
  Abnova Taiwan Corp.

NFKBIB / IKBB antibody

NFKBIB monoclonal antibody (M02), clone 2B11 Western Blot analysis of NFKBIB expression in HL-60 ( Cat # L014V1 ). Mouse IgG 2B11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NFKBIB / IKBB antibody

NFKBIB monoclonal antibody (M03), clone 3E11 Western Blot analysis of NFKBIB expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 3E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NFKBIB / IKBB antibody

NFKBIB monoclonal antibody (M04), clone 3B5 Western Blot analysis of NFKBIB expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 3B5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NFKBIB / IKBB antibody

NFKBIB / IKBB Mouse IgG2a 1G6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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