NFNB antibody

Principal name

NFNB antibody

Alternative names for NFNB antibody

Dihydropteridine reductase, FMN-dependent nitroreductase, dprA, nfsB, nfsl, Oxygen-insensitive NAD(P)H nitroreductase

SwissProt ID

P38489 (Ecoli)

Gene ID

945778 (nfsB)

Available reactivities

Bac (Bacteria)

Background of NFNB antibody

NFNB, also known as NFSB, shows the ability to reduce quinines. This protein is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.

General readings

Jarrom D., et al. (2009) Biochemistry. 48(32):7665-72.
Singleton DC., et al. (2007) Cancer Gene Ther. 14(12):953-67.

5 Item(s)

per page

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NFNB (1-217, His-tag)

NFNB E. coli Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

NFNB (1-217, His-tag)

NFNB E. coli Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

NFNB

NFNB
0.1 mg / €380.00
  Abnova Taiwan Corp.

NFNB

NFNB Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

NFNB

NFNB Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

5 Item(s)

per page
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