NGEF antibody

Principal name

NGEF antibody

Alternative names for NGEF antibody

Ephexin-1, Neuronal guanine nucleotide exchange factor

SwissProt ID

Q8N5V2 (Human)

Gene ID

25791 (NGEF)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of NGEF antibody

EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NGEF antibody

NGEF Mouse IgG2a 6E7 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NGEF antibody

Immunohistochemistry-Paraffin: NGEF Antibody [NBP1-88820] - Immunohistochemical staining of human cerebral cortex shows strong nuclear and cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NGEF (transcript variant 1)

NGEF Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

NGEF

NGEF Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

NGEF

NGEF Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NGEF overexpression lysate

NGEF overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

NGEF overexpression lysate

NGEF overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

7 Item(s)

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