NHEDC2 antibody

Principal name

NHEDC2 antibody

Alternative names for NHEDC2 antibody

NHA2, Mitochondrial sodium / hydrogen exchanger NHA2, Na(+)/H(+) exchanger-like domain-containing protein 2

SwissProt ID

Q5BKR2 (Mouse), Q86UD5 (Human)

Gene ID

133308 (SLC9B2), 97086

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of NHEDC2 antibody

The sodium-proton exchangers (NHE) antiporters of the CPA1 family, catalyze + and H+ exchange. NHE activity is also involved in other cellular events such as cell migration, adhesion and proliferation in response to growth factors. Nhedc2 is a novel member of the CPA family and is the first mitochondrial NHA characterized to date. It is also unique in that it is the first eukaryotic and tissue-specific CPA2 characterized to date. Nhedc2 is localized to the mitochondria, where it mediates +-dependent exchanges in mitochondrial PH and + acetate induced mitochondrial passive swelling. It is strongly upregulated during RANKL-induced osteoclast differentiation in vivo and in vitro. R silencing of this gene reduces osteoclast differentiation and resorption, suggesting that it plays a key role(s) in normal osteoclast differentiation and function.

General readings

Battaglino,R.A., (2008) Bone 42 (1), 180-192

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NHEDC2 antibody

Protein extracts prepared from wild-type mouse bone marrow derived macrophages (BMMs) incubated without (-R, Lane 1, BMMs) or with RANKL (+R, Lane 2, Osteoclasts) were resolved by electrophoresis. The membrane was probed with polyclonal anti-Nhedc2 antibody. Protein was visualized by goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. This antibody recognizes Nhedc2, which runs at approximately 50 kD with predicted molecular weight of 58 kD. Rabbit IgG Poly6485 Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NHEDC2 antibody

WB Suggested Anti-SLC9B2 Antibody Titration: 0.2-1 ug/ml; Positive Control: NTERA2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NHEDC2 antibody

Western Blot analysis of NHEDC2 expression in transfected 293T cell line (H00133308-T01) by NHEDC2 MaxPab polyclonal antibody.

Lane 1: LOC133308 transfected lysate(59.07 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

NHEDC2 antibody

Western Blot analysis of LOC133308 expression in transfected 293T cell line by LOC133308 MaxPab polyclonal antibody.

Lane 1: LOC133308 transfected lysate(59.07 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

NHEDC2 antibody

Human NTERA2; WB Suggested Anti-NHEDC2 Antibody Titration: 0.2-1 ug/ml. Positive Control: NTERA2 cell lysate; NHEDC2 antibody - C-terminal region (ARP53383_P050) in Human NTERA2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

NHEDC2 antibody

Western Blot: NHEDC2 Antibody [NBP1-59579] - This Anti-NHEDC2 antibody was used in Western Blot of NTERA2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

LOC133308 293T Cell Transient Overexpression Lysate(Denatured)

LOC133308 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

7 Item(s)

per page
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