Nicalin antibody

Principal name

Nicalin antibody

Alternative names for Nicalin antibody

NCLN

SwissProt ID

Q5XIA1 (Rat), Q8VCM8 (Mouse), Q969V3 (Human)

Gene ID

56926 (NCLN), 856926 (DMC1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Nicalin antibody

NCLN Antibody: Nicalin, along with its binding partner Nomo, is a novel sigling antagonist to Nodals, sigling factors of the TGF-β superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer's disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.

General readings

Haffner C, Frauli M, Topp S, et al. Nicalin and its binding partner Nomo are novel Nodal signaling antagonists. EMBO J. 2004; 23:3041-50.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Nicalin (N-term) antibody

Immunofluorescence of NCLN in human heart tissue with NCLN antibody at 20 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Nicalin antibody

WB Suggested Anti-NCLN Antibody; Titration: 1.0 ug/ml; Positive Control: ACHN Whole Cell Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Nicalin (N-term) Control Peptide

Western blot analysis in mouse heart tissue lysate with Nicalin / NCLN antibody Cat.-No. AP55643PU-N at 0.5 µg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

Nicalin antibody

NCLN polyclonal antibody (A01), Lot # 060703JCS1. Western Blot analysis of NCLN expression in Daoy. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Nicalin antibody

Western blot analysis of extracts from HepG2/HuvEc cells, using NCLN Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Nicalin antibody

Western blot analysis of extracts from HepG2/HuvEc cells, using NCLN Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Nicalin antibody

Immunohistochemistry-Paraffin: NCLN Antibody [NBP1-81002] - Immunohistochemical staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Nicalin

Nicalin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Nicalin

Nicalin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Nicalin

Nicalin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Nicalin

Nicalin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NCLN overexpression lysate

NCLN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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