NKX2-6 antibody

Principal name

NKX2-6 antibody

Alternative names for NKX2-6 antibody

NKX2F, Nkx-2.6, Homeobox protein Nkx-2.6

SwissProt ID

A6NCS4 (Human), P43688

Gene ID

137814 (NKX2-6), 18092 (Nkx2-6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NKX2-6 antibody

Members of the NK-2 family of homeodomain proteins are key regulators of growth and development in several tissues, including brain, heart and pancreas.Nkx-2.5, also designated cardiac specific homeobox protein (Csx), is a homolog of the Drosophila tinman protein and is essential for normal cardiovascular development. Expression of Nkx-2.5 during cardiomyogenesis is required for cardiac septation, in which a single atrium and ventricle are separated into four chambers. Nkx-2.5 binds to DNA as a monomer, a homodimer or as a heterodimer with Nkx-2.3 or Nkx-2.6, which suggests that the specific protein-protein interactions of Nkx-2.5 are involved in its transcriptional regulatory function. Nkx-2.6, also a homolog of the Drosophila tinman protein, is expressed in the caudal pharyngeal pouches,the caudal heart progenitors, the sinus venosus, the outflow tract of the heart and in a short segment of the gut between stages E8.5 and E10.5 of embryogenesis. Expression of Nkx-2.6 overlaps with that of Nkx-2.5 in the pharynx and heart. However, Nkx-2.6 mutant mice are viable and fertile, which suggests that Nkx-2.6 plays a compensatory function to Nkx-2.5.

General readings

Copeland NG, Jenkins NA, and Harvey RP. The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics 1994; 22:655-6.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NKX2-6 antibody

  Rabbit polyclonal anti-NKX2-6 antibody  
Western blot analysis of extracts from HeLa cells and COLO cells, using NKX26 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NKX2-6 (Center) antibody

  Rabbit Polyclonal NKX2-6 Antibody  
Western blot analysis of NKX2-6 in mouse spleen tissue lysate with NKX2-6 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

NKX2-6 antibody

  Rabbit Polyclonal Anti-Nkx2-6 Antibody  
WB Suggested Anti-Nkx2-6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Mouse Heart Rabbit IgG Purified Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

NKX2-6 antibody

Western blot (WB) analysis of Nkx-2.6 antibody (Cat.-No.: AP01480PU-N) in extracts from COLO cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

NKX2-6 antibody

Western blot analysis of extracts from HeLa/COLO cells, using NKX26 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

NKX2-6 antibody

Western blot analysis of extracts from HeLa/COLO cells, using NKX26 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Nkx2 - mouse gene knockout kit via CRISPR

Nkx2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Nkx2 - mouse gene knockout kit via CRISPR

Nkx2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nkx2 - mouse gene knockout kit via CRISPR

Nkx2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Nkx2 - mouse gene knockout kit via CRISPR

Nkx2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NKX2-6

  Purified recombinant protein of Homo sapiens NK2 transcription factor related, locus 6 (Drosophila) (NKX2-6)  
NKX2-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NKX2 overexpression lysate

NKX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, NKX2 (mGFP-tagged) - Human NK2 transcription factor related, locus 6 (Drosophila) (NKX2-6), 200 uL, >10^7 TU/mL

Lenti ORF particles, NKX2 (mGFP-tagged) - Human NK2 transcription factor related, locus 6 (Drosophila) (NKX2-6), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, NKX2 (Myc-DDK tagged) - Human NK2 transcription factor related, locus 6 (Drosophila) (NKX2-6) , 200 uL, >10^7 TU/mL

Lenti ORF particles, NKX2 (Myc-DDK tagged) - Human NK2 transcription factor related, locus 6 (Drosophila) (NKX2-6) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

14 Item(s)

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