NKX3-1 antibody

Principal name

NKX3-1 antibody

Alternative names for NKX3-1 antibody

NKX3.1, NKX3A, Homeobox protein Nkx-3.1

SwissProt ID

P97436 (Mouse), Q99801 (Human)

Gene ID

4824 (NKX3-1), 18095 (Nkx3-1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Dros (Drosophila), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of NKX3-1 antibody

The homeobox gene Nkx-3.1 is the human homolog of Drosophila bagpipe, which, in conjunction with tinman, determines cell fate in the dorsal mesoderm. In mammalian species, Nkx-3.1 is predominantly expressed in prostate, and it regulates prostate development in response to sonic hedgehog (Shh) signaling by exerting growth-suppressive and differentiating effects on prostatic epithelium. Nkx-3.1 is also expressed at lower levels in other tissues, including the heart and gut, in a Shh independent manner, where it plays a role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate and minor salivary glands. Nkx-3.1 preferentially binds the TAAGTA sequence, which has not been reported for any other NK class homeoprotein. The human Nkx-3.1 gene is located on chromosome 8q21, which frequently undergoes a loss of heterozygosity, and although Nkx-3.1 is not a tumor suppressor gene, it may be a useful marker for benign and malignant prostate epithelium.

General readings

Anderson,P.D., et al. (2012) . Clin. Invest. 122 (5), 1907-1919Tan,P.Y., et al. (2012) Mol. Cell. Biol. 32 (2), 399-414

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-NKX3-1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3 min, UM800087)(1:200) Mouse IgG2a UMAB195 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-NKX3-1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3 min, UM800088)(1:200) Mouse IgG1 UMAB196 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-NKX3-1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3 min, UM800087)(1:200) Mouse IgG2a UMAB195 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-NKX3-1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3 min, UM800088)(1:200) Mouse IgG1 UMAB196 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-NKX3-1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805231) Mouse IgG2b OTI2D11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NKX3-1 antibody

Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining. Mouse IgG2b 4H4 Ascites Hu E, F, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

NKX3-1 antibody

Immunofluorescence of monoclonal antibody to NKX3-1 on NIH/3T3 cell. [antibody concentration 10 ug/ml] Mouse IgG2a 1C7 Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

NKX3-1 antibody

Immunohistochemistry-Paraffin: Nkx3.1 Antibody (4H4) [NBP1-51609] - Immunohistochemical analysis of paraffin-embedded human Liver tissues using NKX3A mAb Mouse IgG2b 4H4 Purified Hu E, F, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

NKX3-1 (N-term) antibody

Human prostate stained with Anti-Nkx3.1, cat# AP15684PU Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

NKX3-1 (N-term) antibody

Human prostate stained with Anti-Nkx3.1, cat# AP15684PU Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

NKX3-1 (N-term) antibody

Human prostate stained with Anti-Nkx3.1, cat# AP15684PU Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

NKX3-1 antibody

Detection of NKX3.1 in mouse testis lysate. ECL detection 1 minute. Mouse Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NKX3-1 antibody

Detection of NKX3.1 in recombinant NKX3.1 protein (36 kDa) using anti-NKX3.1.  The two higher MW bands represent a dimer and a trimer, as these occur in all studies of NKX3.1. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

NKX3-1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using NKX3.1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

NKX3-1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NKX3-1 (RC210374, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NKX3-1. Mouse IgG2b OTI4B12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-NKX3-1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805086) Mouse IgG1 OTI1B4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NKX3-1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NKX3-1 (RC210374, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NKX3-1. Mouse IgG1 OTI1C11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-NKX3-1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805088) Mouse IgG1 OTI6D1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NKX3-1 antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-NKX3-1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805090) Mouse IgG1 OTI3H7 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

NKX3-1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NKX3-1 (RC210374, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NKX3-1. Mouse IgG2a OTI4C11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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